Matches in SemOpenAlex for { <https://semopenalex.org/work/W4244552510> ?p ?o ?g. }
Showing items 1 to 62 of
62
with 100 items per page.
- W4244552510 endingPage "484" @default.
- W4244552510 startingPage "480" @default.
- W4244552510 abstract "Because acute attacks of porphyria may be precipitated by anticonvulsants, a therapeutic dilemma arises when seizures complicate hepatic porphyria. The list of unsafe agents includes barbiturates, primidone, phenytoin, mephenytoin, ethotoin, ethosuximide, methsuximide, phensuximide, and trimethadione. Agents are considered unsafe if they induce experimental porphyria in animals, and short trials in patients are unreliable for screening. Using drug incubation in chick-embryo hepatocyte culture, we found that porphyrin was increased by carbamazepine, clonazepam, and valproate. These agents should probably be avoided or used with caution in porphyric patients. Alternative approaches to acute porphyric attacks with seizures are discussed." @default.
- W4244552510 created "2022-05-12" @default.
- W4244552510 creator A5009180707 @default.
- W4244552510 creator A5083363451 @default.
- W4244552510 date "1981-04-01" @default.
- W4244552510 modified "2023-10-18" @default.
- W4244552510 title "Safety of anticonvulsants in hepatic porphyrias" @default.
- W4244552510 doi "https://doi.org/10.1212/wnl.31.4_part_2.480" @default.
- W4244552510 hasPublicationYear "1981" @default.
- W4244552510 type Work @default.
- W4244552510 citedByCount "23" @default.
- W4244552510 crossrefType "journal-article" @default.
- W4244552510 hasAuthorship W4244552510A5009180707 @default.
- W4244552510 hasAuthorship W4244552510A5083363451 @default.
- W4244552510 hasConcept C118552586 @default.
- W4244552510 hasConcept C126322002 @default.
- W4244552510 hasConcept C2775858608 @default.
- W4244552510 hasConcept C2777940757 @default.
- W4244552510 hasConcept C2777992146 @default.
- W4244552510 hasConcept C2778186239 @default.
- W4244552510 hasConcept C2778337148 @default.
- W4244552510 hasConcept C2779028619 @default.
- W4244552510 hasConcept C2779253243 @default.
- W4244552510 hasConcept C2779426884 @default.
- W4244552510 hasConcept C2779619453 @default.
- W4244552510 hasConcept C2780035454 @default.
- W4244552510 hasConcept C71924100 @default.
- W4244552510 hasConcept C98274493 @default.
- W4244552510 hasConceptScore W4244552510C118552586 @default.
- W4244552510 hasConceptScore W4244552510C126322002 @default.
- W4244552510 hasConceptScore W4244552510C2775858608 @default.
- W4244552510 hasConceptScore W4244552510C2777940757 @default.
- W4244552510 hasConceptScore W4244552510C2777992146 @default.
- W4244552510 hasConceptScore W4244552510C2778186239 @default.
- W4244552510 hasConceptScore W4244552510C2778337148 @default.
- W4244552510 hasConceptScore W4244552510C2779028619 @default.
- W4244552510 hasConceptScore W4244552510C2779253243 @default.
- W4244552510 hasConceptScore W4244552510C2779426884 @default.
- W4244552510 hasConceptScore W4244552510C2779619453 @default.
- W4244552510 hasConceptScore W4244552510C2780035454 @default.
- W4244552510 hasConceptScore W4244552510C71924100 @default.
- W4244552510 hasConceptScore W4244552510C98274493 @default.
- W4244552510 hasIssue "Issue 4, Part 2" @default.
- W4244552510 hasLocation W42445525101 @default.
- W4244552510 hasOpenAccess W4244552510 @default.
- W4244552510 hasPrimaryLocation W42445525101 @default.
- W4244552510 hasRelatedWork W2047410306 @default.
- W4244552510 hasRelatedWork W2057926710 @default.
- W4244552510 hasRelatedWork W2074714060 @default.
- W4244552510 hasRelatedWork W2130113454 @default.
- W4244552510 hasRelatedWork W2135304028 @default.
- W4244552510 hasRelatedWork W2136433429 @default.
- W4244552510 hasRelatedWork W2275340067 @default.
- W4244552510 hasRelatedWork W2398131647 @default.
- W4244552510 hasRelatedWork W34455977 @default.
- W4244552510 hasRelatedWork W4229063249 @default.
- W4244552510 hasVolume "31" @default.
- W4244552510 isParatext "false" @default.
- W4244552510 isRetracted "false" @default.
- W4244552510 workType "article" @default.