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- W4244585890 abstract "Abstract Research in general practice is principally focused on common, chronic medical conditions, covers organizational as well as clinical issues and is a multidisciplinary endeavor. At the same time, conditions seen frequently in particular specialities are relatively uncommon, and this has implications for the statistical performance of diagnostic and screening tests. Generally, biostatistical methods in general practice are characterized by sources of variation operating at various levels, including the primary care center, practitioner, and individual. Both study design and data analysis must make reasonable allowance for this, in particular, in experimental studies where the unit of randomization is a group of individuals. Practical, ethical, and financial constraints mean that a variety of study designs will remain valuable in general practice research, but the central role of the pragmatic randomized trial will continue." @default.
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- W4244585890 date "2005-02-15" @default.
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- W4244585890 title "General Practice" @default.
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- W4244585890 doi "https://doi.org/10.1002/0470011815.b2a08022" @default.
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