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• W4244668851 abstract "In a previous paper the incidence of the sex chromatin in various organs during development was reported. In the present study, the positions of the sex chromatin in the nucleus have been observed in the following tissues taken from 14 human embryos (crown-rump length 7.9-286mm): oral and nasal mucosa, esophagus, intestine, trachea, lung, uterus, vagina, urinary bladder and adrenal.1. Positional patterns of the sex chromatin are classified into the following four main types (cf. Fig. 1).Type I, the sex chromatin is not at all visible in the nucleus, Type II, the sex chromatin is adjacent to the nucleolus, Type III, the sex chromatin is free in the nucleoplasma, Type IV, the sex chromatin is adjacent to the nuclear membrane.In Types II-IV, Subdivisions A-F are made, besides III. D, III. E and III. F.2. Types of the position of sex chromatin in the nucleus of several organs scarcely change during the early fetal stage, and in female embryos Type IV is at 52.8%, Type II at 36.2% and Type III at 1.2% in the average.3. In the middle and the later fetal stages, however, positional changes of the sex chromatin as to different organs occur, so that the organs, mentioned above, group themselves in two main classes.a. The frequency of nuclei of Type IV is remarkably higher than that of Type II, as seen in most organs: oral and nasal mucosa, esophageal epithelium, tracheal and alveolar epithelium, uterine and vaginal lining and inner zone of adrenal cortex. In these organs the stratified epithelium shows difference in the types of sex chromatin position according to its layer. For example, in the esophageal epithelium the distribution patterns are as follows: Type I is chiefly seen in the basal layer, Type II is characteristic in the middle layer and Type IV is remarkable in the superficial layer.b. The frequency of nuclei of Type II is obviously higher than that of Type IV, as seen in the transitional epithelium of the urinary bladder and in the outer zone of adrenal cortex.Characteristic distribution of the types of sex chromatin position, mentioned above, seems to appear when each organ may finally acquire its own morphological as well as functional properties.4. FEULGEN-positive mass, similar to the sex chromatin, is visible in 3-28% of the cell nuclei of embryonal tissues in both sexes. This mass may be identified with so-called ‘nucleolus-associated chromatin (CASPERSSON)’, but its relations to the sex chromatin (especially to Type II) are obscure." @default.
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• W4244668851 date "1965-01-01" @default.
• W4244668851 modified "2023-09-27" @default.
• W4244668851 title "Embryological Studies on the Sex Chromatin in Man" @default.
• W4244668851 doi "https://doi.org/10.1679/aohc1950.25.217" @default.
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