FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4244765485> ?p ?o ?g. }

• W4244765485 endingPage "484" @default.
• W4244765485 startingPage "475" @default.
• W4244765485 abstract "Cadmium is a nephrotoxic metal with no known biological function in man. The diet is the main source of cadmium exposure. Smokers may accumulate more Cd through the inhalation of cadmium-containing tobacco smoke (smoking doubles kidney Cd at age 50) than thru diet. The metal is present in all soils and foods, but is in highest concentrations in shellfish, liver, kidney, oil seeds, cocoa beans, and certain wild mushrooms. However, more than 80% of the diet-cadmium comes, however, from cereals, vegetables, and potatoes. Risk from diet Cd is related to the “bioavailable” Cd, not total Cd in foods. Research has shown that the bioavailability (net absorption) of diet Cd is highly affected by levels of Fe, Zn, Ca, phytate and fiber in diets and foods. Nearly all Cd enrichment in the environment is accompanied by 100-fold higher Zn; soil Zn inhibits both Cd uptake by crops and bioavailability of crop Cd in the intestine for all foods except rice. All foods except rice with relatively high Cd levels also contain high levels of Zn and Fe which inhibit Cd absorption by humans from those foods. Long term consumption of rice home-grown on soils Cd-contaminated by mining or smelting of Zn, Pb or Cu ores has caused the major significant diet Cd risks to humans (other than Cd industry workers). Rice is deficient in Fe, Zn and Ca for adequate human nutrition, greatly increasing Cd absorption from rice-based diets. Essentially all humans who suffered Cd induced kidney disease obtained their excessive dietary Cd from rice grown on mine waste contaminated soils. Cadmium accumulates in the kidney with a very long biological half-life, and the first sign of a toxic effect is renal tubular dysfunction. Prolonged tubular dysfunction lowers Ca absorption causing the “Itai-itai” osteomalacia disease first seen in Japan in 1969. Urinary cadmium serves as a good estimate of Cd accumulation in the kidney. CODEX recommends Cd lifetime exposure from foods should be no higher than 25 μg Cd/kg body weight/month. Studies of a large Japanese urban middle-aged women cohort (with much higher daily Cd intake due to commercial rice grown on contaminated soils) showed that no adverse effects on kidney tubule function occurred while urinary Cd remained ≤ 3 μg Cd/g creatinine, a level which EU toxicologists argued caused early adverse Cd effects. Study of strongly affected Japanese rice farm families showed that clearly adverse renal effects began at 10 μg Cd/g creatinine in urine." @default.
• W4244765485 created "2022-05-12" @default.
• W4244765485 creator A5023243905 @default.
• W4244765485 creator A5084857922 @default.
• W4244765485 date "2019-01-01" @default.
• W4244765485 modified "2023-10-02" @default.
• W4244765485 title "Cadmium Exposure in the Environment: Dietary Exposure, Bioavailability and Renal Effects" @default.
• W4244765485 cites W1568628619 @default.
• W4244765485 cites W1591193326 @default.
• W4244765485 cites W1937685754 @default.
• W4244765485 cites W1969592651 @default.
• W4244765485 cites W1983037167 @default.
• W4244765485 cites W1986544341 @default.
• W4244765485 cites W1987924637 @default.
• W4244765485 cites W1988058457 @default.
• W4244765485 cites W1998160973 @default.
• W4244765485 cites W1998594768 @default.
• W4244765485 cites W2001490805 @default.
• W4244765485 cites W2012536545 @default.
• W4244765485 cites W2069661945 @default.
• W4244765485 cites W2070363398 @default.
• W4244765485 cites W2089256592 @default.
• W4244765485 cites W2103004355 @default.
• W4244765485 cites W2117620078 @default.
• W4244765485 cites W2136474026 @default.
• W4244765485 doi "https://doi.org/10.1016/b978-0-12-409548-9.11746-4" @default.
• W4244765485 hasPublicationYear "2019" @default.
• W4244765485 type Work @default.
• W4244765485 citedByCount "7" @default.
• W4244765485 countsByYear W42447654852020 @default.
• W4244765485 countsByYear W42447654852021 @default.
• W4244765485 countsByYear W42447654852022 @default.
• W4244765485 countsByYear W42447654852023 @default.
• W4244765485 crossrefType "book-chapter" @default.
• W4244765485 hasAuthorship W4244765485A5023243905 @default.
• W4244765485 hasAuthorship W4244765485A5084857922 @default.
• W4244765485 hasConcept C107872376 @default.
• W4244765485 hasConcept C178790620 @default.
• W4244765485 hasConcept C181389837 @default.
• W4244765485 hasConcept C185592680 @default.
• W4244765485 hasConcept C31903555 @default.
• W4244765485 hasConcept C544657597 @default.
• W4244765485 hasConcept C86803240 @default.
• W4244765485 hasConcept C98274493 @default.
• W4244765485 hasConceptScore W4244765485C107872376 @default.
• W4244765485 hasConceptScore W4244765485C178790620 @default.
• W4244765485 hasConceptScore W4244765485C181389837 @default.
• W4244765485 hasConceptScore W4244765485C185592680 @default.
• W4244765485 hasConceptScore W4244765485C31903555 @default.
• W4244765485 hasConceptScore W4244765485C544657597 @default.
• W4244765485 hasConceptScore W4244765485C86803240 @default.
• W4244765485 hasConceptScore W4244765485C98274493 @default.
• W4244765485 hasLocation W42447654851 @default.
• W4244765485 hasOpenAccess W4244765485 @default.
• W4244765485 hasPrimaryLocation W42447654851 @default.
• W4244765485 hasRelatedWork W1993235233 @default.
• W4244765485 hasRelatedWork W2008836778 @default.
• W4244765485 hasRelatedWork W2045298868 @default.
• W4244765485 hasRelatedWork W2146332978 @default.
• W4244765485 hasRelatedWork W2373706959 @default.
• W4244765485 hasRelatedWork W2381767722 @default.
• W4244765485 hasRelatedWork W2752857254 @default.
• W4244765485 hasRelatedWork W3201013370 @default.
• W4244765485 hasRelatedWork W4386052758 @default.
• W4244765485 hasRelatedWork W96679230 @default.
• W4244765485 isParatext "false" @default.
• W4244765485 isRetracted "false" @default.
• W4244765485 workType "book-chapter" @default.