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- W4244833650 abstract "Abstract Background: At present, patients with ocular myasthenia gravis (OMG) are typically treated with systemic drugs. We investigated the use of dexamethasone injected in the peribulbar region or extraocular muscle to treat patients with OMG. Methods: Patients with OMG were given dexamethasone via peribulbar injection or direct injection into the main paralyzed extraocular muscles, once a week, for 4-6 weeks. The severity of diplopia, blepharoptosis, eye position, and eye movement were evaluated before and after treatment. The duration of follow-up time was ≥6 months. Results: Among the 14 patients with OMG who received this treatment, mean age was 38.7 ± 29.7 years. After treatment, symptoms were relieved in 12 patients (85.7%), 1 patient (7.1%) had partial response to treatment, and 1 patient (7.1%) had no response. Two patients (14.2%) experienced symptom recurrence during the follow-up period. Conclusions: Dexamethasone peribulbar or extraocular muscle injection is effective in the treatment of patients with OMG and may replace systemic drug therapy. Trial registration: Chinese Clinical Trial Registry, ChiCTR2000038863, October 7, 2020.Retrospectively registered." @default.
- W4244833650 created "2022-05-12" @default.
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- W4244833650 date "2020-10-22" @default.
- W4244833650 modified "2023-09-28" @default.
- W4244833650 title "Local Use of Dexamethasone in the Treatment of Ocular Myasthenia Gravis" @default.
- W4244833650 doi "https://doi.org/10.21203/rs.3.rs-25812/v3" @default.
- W4244833650 hasPublicationYear "2020" @default.
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