FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4244933265> ?p ?o ?g. }

• W4244933265 endingPage "105" @default.
• W4244933265 startingPage "105" @default.
• W4244933265 abstract "<ns4:p><ns4:bold>Background: </ns4:bold>Herpes simplex virus (HSV) is a widely distributed human pathogen that is known for its ulcerative lesions at the infection site. HSV can cause persistent infection in the host that is often followed by a period of latency within the neurons. Considering the high rate of HIV infection in South Africa, it is important to assess the seroprevalence of HSV with a focus to determine the epidemiological association between HSV-DNA and HIV-1 in the population.</ns4:p><ns4:p> <ns4:bold>Methods: </ns4:bold>A total of 44 sera samples were screened for HSV and HIV-1 using the highly sensitive enzyme-linked immunosorbent assay (ELISA). The ELISA positive samples were characterized using polymerase chain reaction (PCR) to confirm the positivity of both viruses and to further differentiate HSV into HSV-1 and -2. Thereafter, the samples were analysed for relatedness using phylogenetic analysis.</ns4:p><ns4:p> <ns4:bold>Results: </ns4:bold>Of the 44 samples, 36 (81.8%) were positive for HIV-1, while 35 (79.5%) were positive for HSV when screened with ELISA kits. The PCR results, with the use of type specific primers, showed that 4/35 (11.4%) samples were specific for HSV-1 while 30/35 (85.7%) were specific for HSV-2. Statistical analysis performed using the chi-squared goodness-of-fit test showed that there is a significant relationship between HSV-2 and HIV-1 transmission.</ns4:p><ns4:p> <ns4:bold>Conclusions:</ns4:bold>There is a significant relationship between HSV-2 and HIV-1 in the study population. Our study shows that some of the HSV-2 isolates are not related to the clinical isolate SD90e from South Africa, suggesting diversity in HSV-2 viral transmission.</ns4:p>" @default.
• W4244933265 created "2022-05-12" @default.
• W4244933265 creator A5026222638 @default.
• W4244933265 creator A5043271687 @default.
• W4244933265 creator A5087271315 @default.
• W4244933265 date "2021-10-15" @default.
• W4244933265 modified "2023-09-28" @default.
• W4244933265 title "Seroprevalence and characterisation of herpes simplex virus from human immunodeficiency virus in samples collected from two provinces in South Africa: a retrospective study" @default.
• W4244933265 cites W1574060875 @default.
• W4244933265 cites W1592385735 @default.
• W4244933265 cites W1715068327 @default.
• W4244933265 cites W1860328665 @default.
• W4244933265 cites W1973352722 @default.
• W4244933265 cites W1992501950 @default.
• W4244933265 cites W2000302499 @default.
• W4244933265 cites W2004837452 @default.
• W4244933265 cites W2005668584 @default.
• W4244933265 cites W2012671264 @default.
• W4244933265 cites W2014401391 @default.
• W4244933265 cites W2016239796 @default.
• W4244933265 cites W2034892842 @default.
• W4244933265 cites W2036479803 @default.
• W4244933265 cites W2041956556 @default.
• W4244933265 cites W2055467735 @default.
• W4244933265 cites W2059790365 @default.
• W4244933265 cites W2074374845 @default.
• W4244933265 cites W2074620757 @default.
• W4244933265 cites W2095120231 @default.
• W4244933265 cites W2096093282 @default.
• W4244933265 cites W2098084846 @default.
• W4244933265 cites W2108111146 @default.
• W4244933265 cites W2109756901 @default.
• W4244933265 cites W2119895869 @default.
• W4244933265 cites W2122452548 @default.
• W4244933265 cites W2133241248 @default.
• W4244933265 cites W2143639723 @default.
• W4244933265 cites W2144064375 @default.
• W4244933265 cites W2170551349 @default.
• W4244933265 cites W2198528112 @default.
• W4244933265 cites W2272791893 @default.
• W4244933265 cites W2280297988 @default.
• W4244933265 cites W2494756538 @default.
• W4244933265 cites W2513311475 @default.
• W4244933265 cites W2566827527 @default.
• W4244933265 cites W2615226588 @default.
• W4244933265 cites W26731956 @default.
• W4244933265 cites W2740000300 @default.
• W4244933265 cites W2749420302 @default.
• W4244933265 cites W2804241602 @default.
• W4244933265 cites W2804481833 @default.
• W4244933265 cites W2887642843 @default.
• W4244933265 cites W2904269865 @default.
• W4244933265 cites W2912975364 @default.
• W4244933265 cites W2920882630 @default.
• W4244933265 cites W2985465240 @default.
• W4244933265 doi "https://doi.org/10.12688/f1000research.28105.3" @default.
• W4244933265 hasPublicationYear "2021" @default.
• W4244933265 type Work @default.
• W4244933265 citedByCount "0" @default.
• W4244933265 crossrefType "journal-article" @default.
• W4244933265 hasAuthorship W4244933265A5026222638 @default.
• W4244933265 hasAuthorship W4244933265A5043271687 @default.
• W4244933265 hasAuthorship W4244933265A5087271315 @default.
• W4244933265 hasBestOaLocation W42449332651 @default.
• W4244933265 hasConcept C159047783 @default.
• W4244933265 hasConcept C159654299 @default.
• W4244933265 hasConcept C203014093 @default.
• W4244933265 hasConcept C2522874641 @default.
• W4244933265 hasConcept C2778494684 @default.
• W4244933265 hasConcept C2781196997 @default.
• W4244933265 hasConcept C2908647359 @default.
• W4244933265 hasConcept C45189115 @default.
• W4244933265 hasConcept C71924100 @default.
• W4244933265 hasConcept C86803240 @default.
• W4244933265 hasConcept C99454951 @default.
• W4244933265 hasConceptScore W4244933265C159047783 @default.
• W4244933265 hasConceptScore W4244933265C159654299 @default.
• W4244933265 hasConceptScore W4244933265C203014093 @default.
• W4244933265 hasConceptScore W4244933265C2522874641 @default.
• W4244933265 hasConceptScore W4244933265C2778494684 @default.
• W4244933265 hasConceptScore W4244933265C2781196997 @default.
• W4244933265 hasConceptScore W4244933265C2908647359 @default.
• W4244933265 hasConceptScore W4244933265C45189115 @default.
• W4244933265 hasConceptScore W4244933265C71924100 @default.
• W4244933265 hasConceptScore W4244933265C86803240 @default.
• W4244933265 hasConceptScore W4244933265C99454951 @default.
• W4244933265 hasLocation W42449332651 @default.
• W4244933265 hasLocation W42449332652 @default.
• W4244933265 hasOpenAccess W4244933265 @default.
• W4244933265 hasPrimaryLocation W42449332651 @default.
• W4244933265 hasRelatedWork W1425291984 @default.
• W4244933265 hasRelatedWork W1702322095 @default.
• W4244933265 hasRelatedWork W1993339219 @default.
• W4244933265 hasRelatedWork W2038801503 @default.
• W4244933265 hasRelatedWork W2049265285 @default.
• W4244933265 hasRelatedWork W2066091494 @default.
• W4244933265 hasRelatedWork W2073329231 @default.
• W4244933265 hasRelatedWork W2158920391 @default.

• next