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- W4245004139 abstract "To evaluate postapproval outcomes of patients with juxtarenal aortic aneurysms (JRAAs) treated with Zenith Fenestrated Endovascular Graft (zFEN). We reviewed clinical data on consecutive patients treated with zFEN in the US at seven institutions with early commercial access from 7/12 to 12/12. Clinical outcomes and compliance to anatomical guidelines were compared with results of the US fenestrated trial (USFT). Fifty-seven patients were treated. There were significantly more (P < .05) patients with coronary artery disease, myocardial infarction, and preoperative renal insufficiency than in the USFT. Twenty-seven patients (47%) did not meet the USFT anatomic criteria of a >4 mm infrarenal neck, and there were significantly more mesenteric stents (13 vs 0; P < .05) used in this group than in the USFT, reflecting the higher anatomical complexity of these patients. The total operative time was 250.2 ± 14.8 minutes, fluoroscopy time was 68.9 ± 4.47 minutes, and the average contrast volume was 108.6 ± 5.6 mL. Technical success was 100% in regards to aneurysm exclusion, although in two patients the left renal fenestration was not able to be aligned, and one patient had a kinked renal stent that was successfully re-stented. During this time period, there were a total of 10 endoleaks of which two were type 3 and eight were type II (Table). Despite higher rates of comorbidities and more challenging anatomy, early 30-day outcomes of JRAAs treated postapproval with zFEN compare well with USFT data.TablePatient demographics and 30-day outcomesStudy patientszFEN trial patientsP valueNo.5742Age, years73.375.3.76Coronary artery disease, n (%)45 (79)22 (52.4)<.05Chronic obstructive pulmonary disease, n (%)21 (36.8)14 (33.3).83History of myocardial infarction, n (%)34 (59.6)10 (23.8)<.05Technical success, n (%)57 (100)42 (100)1.00Mortality, n (%)1 (1.75)0 (0)1.00Postoperative dialysis, n (%)1 (1.75)0 (0)1.00Endoleak, n109.62 Open table in a new tab" @default.
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- W4245004139 date "2013-11-01" @default.
- W4245004139 modified "2023-10-18" @default.
- W4245004139 title "Post-Approval Outcomes of Juxtarenal Aortic Aneurysms Treated with the Zenith Fenestrated Endovascular Graft" @default.
- W4245004139 doi "https://doi.org/10.1016/j.jvs.2013.08.066" @default.
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