FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4245101639> ?p ?o ?g. }

• W4245101639 endingPage "1088" @default.
• W4245101639 startingPage "1084" @default.
• W4245101639 abstract "Lassa virus glycoprotein is translated as a precursor (pre-GP-C) into the lumen of the endoplasmic reticulum and is cotranslationally cleaved into the signal peptide and GP-C, before GP-C is proteolytically processed into its subunits GP1 and GP2. The signal peptide of pre-GP-C comprises 58 amino acids. The substitution of Lassa virus pre-GP-C signal peptide with another signal peptide still mediates translocation and the release of signal peptide but abolishes the proteolytic cleavage of GP-C into GP1 and GP2. Remarkably, cleavage of GP-C from these hybrid pre-GP-C substrates was restored on coexpression of the wild-type pre-GP-C signal peptide, indicating that the signal peptide functions as a trans-acting factor to promote Lassa virus GP-C processing. To our knowledge, this is the first report on a signal peptide that is essential for proteolytic processing of a secretory pathway protein." @default.
• W4245101639 created "2022-05-12" @default.
• W4245101639 creator A5003467855 @default.
• W4245101639 creator A5003852779 @default.
• W4245101639 creator A5010927081 @default.
• W4245101639 creator A5041614591 @default.
• W4245101639 creator A5057194171 @default.
• W4245101639 creator A5086764947 @default.
• W4245101639 date "2003-10-01" @default.
• W4245101639 modified "2023-10-08" @default.
• W4245101639 title "Identification of Lassa virus glycoprotein signal peptide as a trans-acting maturation factor" @default.
• W4245101639 cites W1548736406 @default.
• W4245101639 cites W1974747471 @default.
• W4245101639 cites W1975085160 @default.
• W4245101639 cites W1979868788 @default.
• W4245101639 cites W1981765089 @default.
• W4245101639 cites W1988537840 @default.
• W4245101639 cites W2018051110 @default.
• W4245101639 cites W2018289835 @default.
• W4245101639 cites W2028858498 @default.
• W4245101639 cites W2044658288 @default.
• W4245101639 cites W2054484042 @default.
• W4245101639 cites W2060997082 @default.
• W4245101639 cites W2077748639 @default.
• W4245101639 cites W2100475845 @default.
• W4245101639 cites W2100837269 @default.
• W4245101639 cites W2107886504 @default.
• W4245101639 cites W2116171543 @default.
• W4245101639 cites W2117761303 @default.
• W4245101639 cites W2122647692 @default.
• W4245101639 cites W2127639686 @default.
• W4245101639 cites W2139833905 @default.
• W4245101639 cites W2142137533 @default.
• W4245101639 cites W2143140715 @default.
• W4245101639 cites W2163443142 @default.
• W4245101639 cites W2171091522 @default.
• W4245101639 doi "https://doi.org/10.1038/sj.embor.embor7400002" @default.
• W4245101639 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14555961" @default.
• W4245101639 hasPublicationYear "2003" @default.
• W4245101639 type Work @default.
• W4245101639 citedByCount "44" @default.
• W4245101639 countsByYear W42451016392016 @default.
• W4245101639 countsByYear W42451016392017 @default.
• W4245101639 countsByYear W42451016392018 @default.
• W4245101639 countsByYear W42451016392019 @default.
• W4245101639 countsByYear W42451016392021 @default.
• W4245101639 countsByYear W42451016392022 @default.
• W4245101639 countsByYear W42451016392023 @default.
• W4245101639 crossrefType "journal-article" @default.
• W4245101639 hasAuthorship W4245101639A5003467855 @default.
• W4245101639 hasAuthorship W4245101639A5003852779 @default.
• W4245101639 hasAuthorship W4245101639A5010927081 @default.
• W4245101639 hasAuthorship W4245101639A5041614591 @default.
• W4245101639 hasAuthorship W4245101639A5057194171 @default.
• W4245101639 hasAuthorship W4245101639A5086764947 @default.
• W4245101639 hasBestOaLocation W42451016392 @default.
• W4245101639 hasConcept C104317684 @default.
• W4245101639 hasConcept C10858879 @default.
• W4245101639 hasConcept C108625454 @default.
• W4245101639 hasConcept C151730666 @default.
• W4245101639 hasConcept C158617107 @default.
• W4245101639 hasConcept C159047783 @default.
• W4245101639 hasConcept C167625842 @default.
• W4245101639 hasConcept C175156509 @default.
• W4245101639 hasConcept C2522874641 @default.
• W4245101639 hasConcept C2777427142 @default.
• W4245101639 hasConcept C2779190341 @default.
• W4245101639 hasConcept C2779281246 @default.
• W4245101639 hasConcept C43369102 @default.
• W4245101639 hasConcept C55493867 @default.
• W4245101639 hasConcept C86803240 @default.
• W4245101639 hasConcept C95444343 @default.
• W4245101639 hasConceptScore W4245101639C104317684 @default.
• W4245101639 hasConceptScore W4245101639C10858879 @default.
• W4245101639 hasConceptScore W4245101639C108625454 @default.
• W4245101639 hasConceptScore W4245101639C151730666 @default.
• W4245101639 hasConceptScore W4245101639C158617107 @default.
• W4245101639 hasConceptScore W4245101639C159047783 @default.
• W4245101639 hasConceptScore W4245101639C167625842 @default.
• W4245101639 hasConceptScore W4245101639C175156509 @default.
• W4245101639 hasConceptScore W4245101639C2522874641 @default.
• W4245101639 hasConceptScore W4245101639C2777427142 @default.
• W4245101639 hasConceptScore W4245101639C2779190341 @default.
• W4245101639 hasConceptScore W4245101639C2779281246 @default.
• W4245101639 hasConceptScore W4245101639C43369102 @default.
• W4245101639 hasConceptScore W4245101639C55493867 @default.
• W4245101639 hasConceptScore W4245101639C86803240 @default.
• W4245101639 hasConceptScore W4245101639C95444343 @default.
• W4245101639 hasIssue "11" @default.
• W4245101639 hasLocation W42451016391 @default.
• W4245101639 hasLocation W42451016392 @default.
• W4245101639 hasLocation W42451016393 @default.
• W4245101639 hasOpenAccess W4245101639 @default.
• W4245101639 hasPrimaryLocation W42451016391 @default.
• W4245101639 hasRelatedWork W1486779406 @default.
• W4245101639 hasRelatedWork W1520794681 @default.
• W4245101639 hasRelatedWork W2035558690 @default.
• W4245101639 hasRelatedWork W2038444889 @default.

• next