FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4245165795> ?p ?o ?g. }

• W4245165795 endingPage "396" @default.
• W4245165795 startingPage "396" @default.
• W4245165795 abstract "Achalasia is the most common and best characterized primary esophageal motility disorder with a prevalence of 10 per 100,000 individuals, with an annual incidence of 0.5 cases per 100,000 individuals. The natural pathology of achalasia is such that progressive neural degeneration leads to dysphagia, a defunctionalized esophagus, and eventually end-stage disease that requires an esophagectomy. Finley and colleagues [1Finley C. Kondra J. Clifton J. Yee J. Finley R. Factors associated with postoperative symptoms after laparoscopic Heller myotomy.Ann Thorac Surg. 2010; 89: 392-396Abstract Full Text Full Text PDF PubMed Scopus (35) Google Scholar] have investigated the effects of initial nonoperative management in short- and long-term symptoms after myotomy for a 14-year period of study. The most concerning finding was that Botox therapy at initial presentation was associated with a higher rate of dysphagia 1 year after surgical myotomy. A surgical concern with Botox is the development of fibrosis leading to difficulty in submucosal dissection during the myotomy and even possible incomplete myotomy. These findings suggest that initial temporizing procedures are not without consequences. Every study has its limitations. This article provides useful information, although ascertainment bias is likely present because all subjective data were recorded by the operating surgeon. There must also be some caution used to interpret the initial treatment data because of the neat separation of the three initial treatments (ie, 62.3% medication, 38.7% pneumatic dilation, and 11.1% Botox). There is no description of overlap between the three treatments, which is common to everyday practice. Half of the patients in this study underwent fundoplication. Many United States' surgeons believe that a myotomy of this extent should be followed by a partial fundoplication to prevent reflux. A prospective randomized trial conducted in the United States on 43 patients demonstrated a lower incidence of reflux without increased dysphagia in patients who underwent myotomy plus Dor compared with myotomy alone [2Richards W.O. Torquati A. Holzman M.D. et al.Heller myotomy versus Heller myotomy with Dor fundoplication for achalasia: a prospective randomized double-blind trial.Ann Surg. 2004; 240: 405-412Crossref PubMed Scopus (423) Google Scholar]. Despite this data, the role of fundoplication remains controversial, especially outside the United States. The myotomy does not reverse the underlying pathophysiology of neural degeneration, but it does convert the esophagus into a passive conduit dependent on gravity for evacuation. A balance between obtaining a complete myotomy and the avoidance of excessive reflux is the primary goal. Delay in surgical treatment will only increase the likelihood of long-term sequela (ie, mega-esophagus, thereby leading to esophagectomy for end-stage disease). Finley and colleagues [1Finley C. Kondra J. Clifton J. Yee J. Finley R. Factors associated with postoperative symptoms after laparoscopic Heller myotomy.Ann Thorac Surg. 2010; 89: 392-396Abstract Full Text Full Text PDF PubMed Scopus (35) Google Scholar] provide additional evidence to support the early treatment of achalasia by surgical intervention rather than exhaustive conservative treatments. Factors Associated With Postoperative Symptoms After Laparoscopic Heller MyotomyThe Annals of Thoracic SurgeryVol. 89Issue 2PreviewOur objective is to ascertain if preoperative and perioperative treatments affect the short- and long-term symptom frequency or symptom scores for dysphagia, regurgitation, and heartburn in patients with laparoscopic Heller myotomy for achalasia. Full-Text PDF" @default.
• W4245165795 created "2022-05-12" @default.
• W4245165795 creator A5060347349 @default.
• W4245165795 date "2010-02-01" @default.
• W4245165795 modified "2023-09-25" @default.
• W4245165795 title "Invited Commentary" @default.
• W4245165795 doi "https://doi.org/10.1016/j.athoracsur.2009.11.040" @default.
• W4245165795 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20103307" @default.
• W4245165795 hasPublicationYear "2010" @default.
• W4245165795 type Work @default.
• W4245165795 citedByCount "0" @default.
• W4245165795 crossrefType "journal-article" @default.
• W4245165795 hasAuthorship W4245165795A5060347349 @default.
• W4245165795 hasConcept C121608353 @default.
• W4245165795 hasConcept C126322002 @default.
• W4245165795 hasConcept C141071460 @default.
• W4245165795 hasConcept C2775862295 @default.
• W4245165795 hasConcept C2776928572 @default.
• W4245165795 hasConcept C2777297899 @default.
• W4245165795 hasConcept C2777819096 @default.
• W4245165795 hasConcept C2779742542 @default.
• W4245165795 hasConcept C2779958274 @default.
• W4245165795 hasConcept C2780596822 @default.
• W4245165795 hasConcept C2780942740 @default.
• W4245165795 hasConcept C61434518 @default.
• W4245165795 hasConcept C71924100 @default.
• W4245165795 hasConceptScore W4245165795C121608353 @default.
• W4245165795 hasConceptScore W4245165795C126322002 @default.
• W4245165795 hasConceptScore W4245165795C141071460 @default.
• W4245165795 hasConceptScore W4245165795C2775862295 @default.
• W4245165795 hasConceptScore W4245165795C2776928572 @default.
• W4245165795 hasConceptScore W4245165795C2777297899 @default.
• W4245165795 hasConceptScore W4245165795C2777819096 @default.
• W4245165795 hasConceptScore W4245165795C2779742542 @default.
• W4245165795 hasConceptScore W4245165795C2779958274 @default.
• W4245165795 hasConceptScore W4245165795C2780596822 @default.
• W4245165795 hasConceptScore W4245165795C2780942740 @default.
• W4245165795 hasConceptScore W4245165795C61434518 @default.
• W4245165795 hasConceptScore W4245165795C71924100 @default.
• W4245165795 hasIssue "2" @default.
• W4245165795 hasLocation W42451657951 @default.
• W4245165795 hasLocation W42451657952 @default.
• W4245165795 hasOpenAccess W4245165795 @default.
• W4245165795 hasPrimaryLocation W42451657951 @default.
• W4245165795 hasRelatedWork W1452895882 @default.
• W4245165795 hasRelatedWork W1821972697 @default.
• W4245165795 hasRelatedWork W1970590385 @default.
• W4245165795 hasRelatedWork W1980602303 @default.
• W4245165795 hasRelatedWork W2031442326 @default.
• W4245165795 hasRelatedWork W2076357993 @default.
• W4245165795 hasRelatedWork W2578812995 @default.
• W4245165795 hasRelatedWork W4210693775 @default.
• W4245165795 hasRelatedWork W80286786 @default.
• W4245165795 hasRelatedWork W2184768059 @default.
• W4245165795 hasVolume "89" @default.
• W4245165795 isParatext "false" @default.
• W4245165795 isRetracted "false" @default.
• W4245165795 workType "article" @default.