Matches in SemOpenAlex for { <https://semopenalex.org/work/W4245282005> ?p ?o ?g. }
Showing items 1 to 62 of
62
with 100 items per page.
- W4245282005 endingPage "2572" @default.
- W4245282005 startingPage "2567" @default.
- W4245282005 abstract "<h3>Background:</h3> Nicotine replacement therapies have proved to be of value in smoking cessation. However, not all smokers can use the nicotine gum or nicotine patch owing to side effects. In addition, the absorption of nicotine from these formulas is slow compared with smoking. A nicotine nasal spray delivers nicotine more rapidly. The objective of this study was to evaluate the efficacy and safety of the nicotine nasal spray for smoking cessation. <h3>Methods:</h3> Subjects were recruited through advertisements in newspapers and among patients referred to the smoking cessation clinic at Sahlgren's Hospital, Göteborg, Sweden. Two hundred forty-eight smokers were treated in small groups with eight counseling sessions over 6 weeks. At their first group session, subjects were randomized to a group receiving nicotine spray (n=125), 0.5 mg of nicotine per single spray, or to a placebo group (n=123). The procedure was double blind. Success rates were measured up to 12 months. The nonsmoking status was verified by expired carbon monoxide less than 10 ppm. <h3>Results:</h3> Significantly more subjects in the nicotine group were continuously abstinent for 12 months than in the placebo group (27% vs 15%; odds ratio, 2.16; 95% confidence interval, 1.15 to 4.12). Ten of the 34 abstinent subjects in the nicotine group used the spray for 1 year. Mild or moderate side effects were rather frequent for both sprays, but they were significantly more for the nicotine spray. Subjects with high scores (><i>7</i>) on Fagerström's tolerance questionnaire had a significantly lower success rate with placebo than with the nicotine spray. For subjects with low scores, there was no difference. Conclusion: Nicotine nasal spray in combination with group treatment is an effective aid to smoking cessation. (Arch Intern Med. 1994;154:2567-2572)" @default.
- W4245282005 created "2022-05-12" @default.
- W4245282005 creator A5088515111 @default.
- W4245282005 date "1994-11-28" @default.
- W4245282005 modified "2023-09-25" @default.
- W4245282005 title "Effect of nicotine nasal spray on smoking cessation. A randomized, placebo-controlled, double-blind study" @default.
- W4245282005 doi "https://doi.org/10.1001/archinte.154.22.2567" @default.
- W4245282005 hasPublicationYear "1994" @default.
- W4245282005 type Work @default.
- W4245282005 citedByCount "23" @default.
- W4245282005 crossrefType "journal-article" @default.
- W4245282005 hasAuthorship W4245282005A5088515111 @default.
- W4245282005 hasConcept C126322002 @default.
- W4245282005 hasConcept C142724271 @default.
- W4245282005 hasConcept C156957248 @default.
- W4245282005 hasConcept C204787440 @default.
- W4245282005 hasConcept C27081682 @default.
- W4245282005 hasConcept C2776087441 @default.
- W4245282005 hasConcept C2776319443 @default.
- W4245282005 hasConcept C2777843972 @default.
- W4245282005 hasConcept C2779547902 @default.
- W4245282005 hasConcept C2780973058 @default.
- W4245282005 hasConcept C42219234 @default.
- W4245282005 hasConcept C44249647 @default.
- W4245282005 hasConcept C71924100 @default.
- W4245282005 hasConcept C85663871 @default.
- W4245282005 hasConcept C98274493 @default.
- W4245282005 hasConceptScore W4245282005C126322002 @default.
- W4245282005 hasConceptScore W4245282005C142724271 @default.
- W4245282005 hasConceptScore W4245282005C156957248 @default.
- W4245282005 hasConceptScore W4245282005C204787440 @default.
- W4245282005 hasConceptScore W4245282005C27081682 @default.
- W4245282005 hasConceptScore W4245282005C2776087441 @default.
- W4245282005 hasConceptScore W4245282005C2776319443 @default.
- W4245282005 hasConceptScore W4245282005C2777843972 @default.
- W4245282005 hasConceptScore W4245282005C2779547902 @default.
- W4245282005 hasConceptScore W4245282005C2780973058 @default.
- W4245282005 hasConceptScore W4245282005C42219234 @default.
- W4245282005 hasConceptScore W4245282005C44249647 @default.
- W4245282005 hasConceptScore W4245282005C71924100 @default.
- W4245282005 hasConceptScore W4245282005C85663871 @default.
- W4245282005 hasConceptScore W4245282005C98274493 @default.
- W4245282005 hasIssue "22" @default.
- W4245282005 hasLocation W42452820051 @default.
- W4245282005 hasOpenAccess W4245282005 @default.
- W4245282005 hasPrimaryLocation W42452820051 @default.
- W4245282005 hasRelatedWork W1675801058 @default.
- W4245282005 hasRelatedWork W1971896294 @default.
- W4245282005 hasRelatedWork W1983632832 @default.
- W4245282005 hasRelatedWork W1984116490 @default.
- W4245282005 hasRelatedWork W1985796466 @default.
- W4245282005 hasRelatedWork W2004833034 @default.
- W4245282005 hasRelatedWork W2006898082 @default.
- W4245282005 hasRelatedWork W2162622117 @default.
- W4245282005 hasRelatedWork W4240552750 @default.
- W4245282005 hasRelatedWork W2014564112 @default.
- W4245282005 hasVolume "154" @default.
- W4245282005 isParatext "false" @default.
- W4245282005 isRetracted "false" @default.
- W4245282005 workType "article" @default.