Matches in SemOpenAlex for { <https://semopenalex.org/work/W4245356013> ?p ?o ?g. }
Showing items 1 to 69 of
69
with 100 items per page.
- W4245356013 abstract "Abstract Background For the microorganisms on the paper surface, the lack of water is one of the most important stress factors. A strain of Bacillus megaterium FDU301 was isolated from plaques on the paper surface using the culture medium with polyethylene glycol 200 (PEG200) to simulate arid condition. Global transcriptomic analysis of B. megaterium FDU301 grown under normal and the simulated arid conditions was performed via RNA-seq technology to identify genes involved in arid stress adaptation. Results The transcriptome of B. megaterium FDU301 grown in LB medium under arid (15% PEG200 (w/w)) and normal conditions were compared. A total of 2941 genes were differentially expressed, including 1422 genes up-regulated and 1519 genes down-regulated under arid conditions. Oxidative stress-responsive regulatory genes perR , fur , and tipA were significantly up-regulated, along with DNA protecting protein ( dps ), catalase ( katE ). Genes related to Fe 2+ uptake ( feoB ), spore formation stage II ( spoIIB , spoIIE , spoIIGA ), small acid-soluble spore protein ( sspD ), and biosynthesis of compatible solute ectoine ( ectB , ectA ) were also highly expressed to various degrees. Meanwhile, oxidative phosphorylation-related genes ( atpB, atpE, atpF, atpH, atpA, atpG , atpD , atpC ) and glycolysis-related genes ( pgk , tpiA , frmA ) were significantly down-regulated. Conclusion This is the first report about transcriptomic analysis of a B. megaterium to explore the mechanism of arid resistance. Major changes in transcription were seen in the arid condition simulated by PEG200 (15%), with the most important one being the genes related to oxidative stress. The results showed the complex mechanism for bacteria to adapt to arid stress." @default.
- W4245356013 created "2022-05-12" @default.
- W4245356013 creator A5001883421 @default.
- W4245356013 creator A5004637425 @default.
- W4245356013 creator A5039056602 @default.
- W4245356013 creator A5039280072 @default.
- W4245356013 creator A5049445264 @default.
- W4245356013 creator A5062321212 @default.
- W4245356013 creator A5063599261 @default.
- W4245356013 creator A5082312520 @default.
- W4245356013 date "2020-08-17" @default.
- W4245356013 modified "2023-09-23" @default.
- W4245356013 title "Transcriptional response of Bacillus megaterium FDU301 to PEG200-mediated arid stress" @default.
- W4245356013 doi "https://doi.org/10.21203/rs.3.rs-58150/v1" @default.
- W4245356013 hasPublicationYear "2020" @default.
- W4245356013 type Work @default.
- W4245356013 citedByCount "0" @default.
- W4245356013 crossrefType "posted-content" @default.
- W4245356013 hasAuthorship W4245356013A5001883421 @default.
- W4245356013 hasAuthorship W4245356013A5004637425 @default.
- W4245356013 hasAuthorship W4245356013A5039056602 @default.
- W4245356013 hasAuthorship W4245356013A5039280072 @default.
- W4245356013 hasAuthorship W4245356013A5049445264 @default.
- W4245356013 hasAuthorship W4245356013A5062321212 @default.
- W4245356013 hasAuthorship W4245356013A5063599261 @default.
- W4245356013 hasAuthorship W4245356013A5082312520 @default.
- W4245356013 hasBestOaLocation W42453560131 @default.
- W4245356013 hasConcept C104317684 @default.
- W4245356013 hasConcept C150194340 @default.
- W4245356013 hasConcept C162317418 @default.
- W4245356013 hasConcept C26448091 @default.
- W4245356013 hasConcept C2779815552 @default.
- W4245356013 hasConcept C2780929338 @default.
- W4245356013 hasConcept C2780989563 @default.
- W4245356013 hasConcept C515207424 @default.
- W4245356013 hasConcept C523546767 @default.
- W4245356013 hasConcept C54355233 @default.
- W4245356013 hasConcept C55493867 @default.
- W4245356013 hasConcept C86803240 @default.
- W4245356013 hasConceptScore W4245356013C104317684 @default.
- W4245356013 hasConceptScore W4245356013C150194340 @default.
- W4245356013 hasConceptScore W4245356013C162317418 @default.
- W4245356013 hasConceptScore W4245356013C26448091 @default.
- W4245356013 hasConceptScore W4245356013C2779815552 @default.
- W4245356013 hasConceptScore W4245356013C2780929338 @default.
- W4245356013 hasConceptScore W4245356013C2780989563 @default.
- W4245356013 hasConceptScore W4245356013C515207424 @default.
- W4245356013 hasConceptScore W4245356013C523546767 @default.
- W4245356013 hasConceptScore W4245356013C54355233 @default.
- W4245356013 hasConceptScore W4245356013C55493867 @default.
- W4245356013 hasConceptScore W4245356013C86803240 @default.
- W4245356013 hasLocation W42453560131 @default.
- W4245356013 hasLocation W42453560132 @default.
- W4245356013 hasLocation W42453560133 @default.
- W4245356013 hasOpenAccess W4245356013 @default.
- W4245356013 hasPrimaryLocation W42453560131 @default.
- W4245356013 hasRelatedWork W17489470 @default.
- W4245356013 hasRelatedWork W20671236 @default.
- W4245356013 hasRelatedWork W23564805 @default.
- W4245356013 hasRelatedWork W32524361 @default.
- W4245356013 hasRelatedWork W3337489 @default.
- W4245356013 hasRelatedWork W39657844 @default.
- W4245356013 hasRelatedWork W4615924 @default.
- W4245356013 hasRelatedWork W7554588 @default.
- W4245356013 hasRelatedWork W8685363 @default.
- W4245356013 hasRelatedWork W4476469 @default.
- W4245356013 isParatext "false" @default.
- W4245356013 isRetracted "false" @default.
- W4245356013 workType "article" @default.