Matches in SemOpenAlex for { <https://semopenalex.org/work/W4245372223> ?p ?o ?g. }
Showing items 1 to 65 of
65
with 100 items per page.
- W4245372223 endingPage "64" @default.
- W4245372223 startingPage "57" @default.
- W4245372223 abstract "Gilles de la Tourette syndrome (GTS) is a sensorimotor disorder where the sensitivity to external and internal stimuli might be increased and unwanted responses to such stimuli cannot be sufficiently suppressed.Transcranial magnetic stimulation (TMS) studies indicate that, at rest, axonal excitability of cortico-spinal neurons and intra-cortical inter-neurons was consistently normal in GTS. However, synaptic excitability in cortico-spinal neurons and the SICI circuit may be lower than normal. In addition, an electrophysiological marker of sensory motor integration, SAI, was reduced in the baseline state consistent with reduced efficiency of synaptic inhibition. Given the possible influence of sensory inputs in triggering the release of tics reduced SAI may be a direct physiological reflection of increased access of sensory input to motor output in GTS. Experiments examining control of voluntary movements revealed that in GTS motor cortex excitability increases less than in controls when preparing a movement even though intra-cortical inhibition (i.e. SICI) normalises.In GTS the gain of many motor circuits may be reduced and hence less sensitive to small changes in input from other areas. These cortical changes may constitute an adaptive response to abnormal basal ganglia-motor cortex inputs." @default.
- W4245372223 created "2022-05-12" @default.
- W4245372223 creator A5041543470 @default.
- W4245372223 creator A5089989540 @default.
- W4245372223 date "2013-01-01" @default.
- W4245372223 modified "2023-09-30" @default.
- W4245372223 title "Transcranial Magnetic Stimulation Studies of Sensorimotor Networks in Tourette Syndrome" @default.
- W4245372223 doi "https://doi.org/10.1155/2013/349137" @default.
- W4245372223 hasPublicationYear "2013" @default.
- W4245372223 type Work @default.
- W4245372223 citedByCount "35" @default.
- W4245372223 countsByYear W42453722232014 @default.
- W4245372223 countsByYear W42453722232015 @default.
- W4245372223 countsByYear W42453722232016 @default.
- W4245372223 countsByYear W42453722232017 @default.
- W4245372223 countsByYear W42453722232018 @default.
- W4245372223 countsByYear W42453722232019 @default.
- W4245372223 countsByYear W42453722232020 @default.
- W4245372223 countsByYear W42453722232021 @default.
- W4245372223 countsByYear W42453722232022 @default.
- W4245372223 crossrefType "journal-article" @default.
- W4245372223 hasAuthorship W4245372223A5041543470 @default.
- W4245372223 hasAuthorship W4245372223A5089989540 @default.
- W4245372223 hasBestOaLocation W42453722231 @default.
- W4245372223 hasConcept C118552586 @default.
- W4245372223 hasConcept C15744967 @default.
- W4245372223 hasConcept C169760540 @default.
- W4245372223 hasConcept C24998067 @default.
- W4245372223 hasConcept C25457674 @default.
- W4245372223 hasConcept C2777026814 @default.
- W4245372223 hasConcept C2777200579 @default.
- W4245372223 hasConcept C2778373776 @default.
- W4245372223 hasConcept C2778581513 @default.
- W4245372223 hasConcept C94487597 @default.
- W4245372223 hasConceptScore W4245372223C118552586 @default.
- W4245372223 hasConceptScore W4245372223C15744967 @default.
- W4245372223 hasConceptScore W4245372223C169760540 @default.
- W4245372223 hasConceptScore W4245372223C24998067 @default.
- W4245372223 hasConceptScore W4245372223C25457674 @default.
- W4245372223 hasConceptScore W4245372223C2777026814 @default.
- W4245372223 hasConceptScore W4245372223C2777200579 @default.
- W4245372223 hasConceptScore W4245372223C2778373776 @default.
- W4245372223 hasConceptScore W4245372223C2778581513 @default.
- W4245372223 hasConceptScore W4245372223C94487597 @default.
- W4245372223 hasIssue "1" @default.
- W4245372223 hasLocation W42453722231 @default.
- W4245372223 hasLocation W42453722232 @default.
- W4245372223 hasOpenAccess W4245372223 @default.
- W4245372223 hasPrimaryLocation W42453722231 @default.
- W4245372223 hasRelatedWork W1980734881 @default.
- W4245372223 hasRelatedWork W2013085605 @default.
- W4245372223 hasRelatedWork W2033092191 @default.
- W4245372223 hasRelatedWork W2095634144 @default.
- W4245372223 hasRelatedWork W2140690464 @default.
- W4245372223 hasRelatedWork W2158240393 @default.
- W4245372223 hasRelatedWork W2334628157 @default.
- W4245372223 hasRelatedWork W2414288209 @default.
- W4245372223 hasRelatedWork W3080776928 @default.
- W4245372223 hasRelatedWork W4245372223 @default.
- W4245372223 hasVolume "27" @default.
- W4245372223 isParatext "false" @default.
- W4245372223 isRetracted "false" @default.
- W4245372223 workType "article" @default.