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- W4245421656 abstract "The aim of this study was to clarify whether amniotic fluid macrophage colony-stimulating factor (M-CSF) is related to placental development and fetal growth. Maternal serum and amniotic fluid M-CSF levels were analyzed in 22 pregnant women (seven intrauterine growth retardation (IUGR) complicated and 15 normal pregnancies) at 33–40 weeks’ gestation. Amniotic fluid was obtained by transabdominal amniocentesis performed under ultrasonographic guidance. The mean amniotic fluid M-CSF level of the IUGR-complicated pregnancy group (5.0±1.4 ng/ml) was significantly lower (P<0.05) than that of the normal pregnancy group (7.4±1.6 ng/ml). All the IUGR-complicated pregnant women subsequently delivered small-for-gestational-age (SGA) infants with significantly lower placental weights than those of the normal infants. There was no significant correlation between amniotic fluid M-CSF levels and gestational age in the normal pregnancy group. The same scattergram showed the amniotic fluid M-CSF levels of the IUGR-complicated pregnancy group tended to be lower than those of the normal pregnancy group at 33–40 weeks’ gestation. The results suggested that amniotic fluid M-CSF was one of the regulators of human placental development and was related to fetal growth." @default.
- W4245421656 created "2022-05-12" @default.
- W4245421656 date "1998-04-01" @default.
- W4245421656 modified "2023-09-26" @default.
- W4245421656 title "Abstract" @default.
- W4245421656 doi "https://doi.org/10.1016/s0165-0378(98)00007-2" @default.
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