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- W4245514116 abstract "Late onset Alzheimer's disease (Alz) affects 40 to 50% of older populations of prosperous nations. Advancing Alz eventually renders the aficted helpless and without memory. Other elders have some reduction in cognition but sustain sufcient capabilities to not be helpless and retain sufcient cognition to live well until their fatal diseases. Despite decades of sound research and as many as 200 clinical trials of putative treatments to halt advancing Alz, all attempts failed to yield an effective medication. Epidemiological research has identied many correlates (risk-factors) of developing Alz. It is posited that an accumulation of the consequences of the various risk-factors is sufcient to induce Alz. Possibly, different combinations of risks can cause sufcient chaos of the brain's physiology to be the conditions starting and advancing Alz. For example, insufcient circulating B-vitamins, manifest as hyperhomocysteinemia, and regularly taking of drugs with severe anticholinergic burdens could cause such wide-spread effects to be a setting condition for developing Alz. Both potential setting conditions can be rectied hence could prevent the development of Alz. Other combinations of risks might be causal and might be treatable, hence preventing Alz." @default.
- W4245514116 created "2022-05-12" @default.
- W4245514116 creator A5091175308 @default.
- W4245514116 date "2021-03-01" @default.
- W4245514116 modified "2023-09-27" @default.
- W4245514116 title "CAUSES OF ALZHEIMER'S DISEASE (Alz) AND POTENTIAL REMEDIES" @default.
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- W4245514116 doi "https://doi.org/10.36106/6846441" @default.
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