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- W4245565742 abstract "Einfaches Ersetzen einer 2′-OH- durch eine 2′-OMe-Gruppe bewirkt bei bestimmten RNA-Strukturen eine merkliche Verstärkung wichtiger Solut-Solvens-Wechselwirkungen. Moleküldynamiksimulationen enthüllten die Komplexität der mit dem Einbringen hydrophober Gruppen in hydrophile Systeme verbundenen Effekte (im gezeigten 2′-OMe(GpC)-Basenpaar ist ein verbrückendes Wassermolekül mit langer Residenzzeit in der kleinen Schleife mit einem Pfeil markiert). Grün=Cytosin-Gerüst, schwarz=Guanin-Gerüst, rot=Sauerstoffatome von Wasser und den Carbonylgruppen der kleinen Schleife, blau=Stickstoffatome der kleinen Schleife. Supporting information for this article is available on the WWW under http://www.angewandte.com or from the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article." @default.
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- W4245565742 date "2001-12-17" @default.
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- W4245565742 title "Hydrophobic Groups Stabilize the Hydration Shell of 2′-O-Methylated RNA Duplexes" @default.
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