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- W4245748440 abstract "At a meeting of the Middlesex County Medical Society in the late 1940s, an audience of more than 200 physicians heard about the various therapies for hyperthyroidism. Edwin B. Astwood, Ted to most at his own request, spoke about the new medical therapy he had devised a few years before, the thiourylene derivatives thiouracil and propylthiouracil (PTU) or, as he called them, anti-thyroid drugs (ATD). Astwood and his colleagues realized that the availability of a drug which would reliably enlarge the thyroid gland could provide a way of untangling problems in thyroid physiology and perhaps elucidate the pathophysiology of goiter. They pursued thyroid physiology and medicine and took full advantage of radioactive iodine when it became available as a physiologic marker and a treatment. They studied literally hundreds of anti-thyroid drugs in a search for the one with the most potent action and the least toxicity." @default.
- W4245748440 created "2022-05-12" @default.
- W4245748440 date "2016-02-12" @default.
- W4245748440 modified "2023-09-23" @default.
- W4245748440 title "Edwin B. Astwood (1909–1976)" @default.
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- W4245748440 doi "https://doi.org/10.1002/9781119205791.ch86" @default.
- W4245748440 hasPublicationYear "2016" @default.
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