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• W4245840903 startingPage "596" @default.
• W4245840903 abstract "The majority of candidate recombinant therapeutics are glycoproteins. Four aspects of glycobiology are requisite if the full potential of such reagents is to be realised: an understanding of glycan biosynthesis and its regulation, rapid and sensitive oligosaccharide analytical techniques, determination of structure-function relationships in protein-linked carbohydrate; and manufacturing systems where product glycosylation is manipulable and consistent. The past year has seen significant progress in all of these areas, exemplified by the approval of glycosylation-engineered glucocerebrosidase for clinical use in replacement therapy of Gaucher's disease." @default.
• W4245840903 created "2022-05-12" @default.
• W4245840903 creator A5059763299 @default.
• W4245840903 date "1993-10-01" @default.
• W4245840903 modified "2023-10-10" @default.
• W4245840903 title "Glycosylation" @default.
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• W4245840903 doi "https://doi.org/10.1016/0958-1669(93)90083-9" @default.
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