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- W4245884158 abstract "Imagine having to remember to breathe, as in the myth of Ondine, who was cursed to think consciously of breathing even in sleep. The term “Ondine’s curse” has been applied to the congenital central hypoventilation syndrome (CCHS), a condition in which children hypoventilate and retain carbon dioxide (especially in sleep), have prominent apneas, and have a severely diminished carbon dioxide chemoreflex (the increase in breathing in response to elevated carbon dioxide levels). The cause of CCHS is a mutation in PHOX2B that affects a single amino acid in the PHOX2B protein. When this mutation is introduced into a mouse, much . . ." @default.
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- W4245884158 date "2015-08-06" @default.
- W4245884158 modified "2023-10-17" @default.
- W4245884158 title "Ondine Undone" @default.
- W4245884158 doi "https://doi.org/10.1056/nejmcibr1507734" @default.
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