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- W4246007713 abstract "The uses of available record systems in epidemiologic studies of reproductive toxicology are described with reference to New York State. The available record systems (and relevant reproductive end points) described include: a newborn screening program I-or metabolic diseases and hemoglobinopathies (relevant to point mutations); chromosome registries and prenatal cytogeneties (for chromosome anomalies); live birth certificates (for birth defects, birthweight, sex ratio, etc); fetal death certificates (for spontaneous fetal deaths); and a statewide cancer registry (for childhood cancers and transplacental carcinogenesis). The uses and limitations of these record systems are discussed, along with examples of their use in descriptive and analytic epidemiologic studies. Descriptive studies outlined include investigations at temporal and geographic trends in birth defects, birth weight, and fetal deaths, with reference to environmental questions (eg. Love Canal, nuclear power plants). Analytic studies described concern parental occupation in relation to specific birth defects (neural tube defects and Down syndrome) and maternal use or contraceptive drugs." @default.
- W4246007713 created "2022-05-12" @default.
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- W4246007713 date "1983-01-01" @default.
- W4246007713 modified "2023-10-17" @default.
- W4246007713 title "Uses of Available Record Systems in Epidemiologic Studies of Reproductive Toxicology" @default.
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- W4246007713 doi "https://doi.org/10.1002/ajim.1983.4.1-2.329" @default.
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