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- W4246014288 abstract "Background and Objectives: In this study we investigated whether platelet activation during apheresis results in the binding of platelets to white blood cells. Material and Methods: Analysis of platelet–leukocyte interaction was performed using multiparameter, three–color flow cytometry. Results: Over the duration of the procedure, there was an increase in the surface expression of CD62p (P–selectin) and CD63 (p<0.05), and also in the binding of platelets to monocytes (p<0.05), neutrophilic granulocytes (p<0.05) and to CD3+ cells (initially to a low degree; p<0.05). Platelet binding to CD19+ cells did not change significantly. Conclusion: This study demonstrates that platelets become activated during apheresis and that following this process, interaction with monocytes and neutrophilic granulocytes occurs." @default.
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- W4246014288 date "2000-03-01" @default.
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- W4246014288 title "Extracorporeal Plateletpheresis Induces the Interaction of Activated Platelets with White Blood Cells" @default.
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- W4246014288 doi "https://doi.org/10.1046/j.1423-0410.2000.7820101.x" @default.
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