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- W4246264088 abstract "Abstract Achondroplasia is the most common of the skeletal dysplasias, arising in approximately 1 in 26,000 individuals. Most individuals with achondroplasia can be expected to have a normal life expectancy. However, they are at increased risk for a variety of medical sequelae, most of which are explicable on the basis of abnormalities of growth of cartilaginous bone or disproportionate growth of cartilaginous bone when compared with other contiguous tissues. Issues of concern include growth, motoric development, adaptive needs, hydrocephalus, cervicomedullary junction constriction, restrictive and obstructive pulmonary disease, middle ear dysfunction, kyphosis, lumbosacral spinal stenosis, bowing of the legs, and anesthetic risks. The natural history of achondroplasia can be beneficially modified by timely anticipatory medical care." @default.
- W4246264088 created "2022-05-12" @default.
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- W4246264088 date "2005-01-14" @default.
- W4246264088 modified "2023-10-13" @default.
- W4246264088 title "Achondroplasia" @default.
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