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- W4246275163 abstract "Biofluid choking, a compressible fluid flow effect, occurs anywhere in the circulatory system including vasa vasorum when the blood/biofluid velocity is equal or above to the local velocity of sound. The choking and unchoking could occur due to the variations in the blood pressure-ratio (BPR) and blood/biofluid heat capacity ratio (BHCR). At the choked condition, Blood pressure ratio (SBP / DBP) is a unique function of BHCR (Cp/Cv). A model capable to predict the lower critical hemorrhage index (LCHI) correlating with BPR and BHCR is developed herein for forecasting the risk of stroke and myocardial infarction (MI) through in silico studies. Through in vitro studies LCHI is predicted for healthy subjects. Using aspirin to reduce viscosity augment Reynolds number, which leads to high turbulence and enhanced boundary layer blockage creating an early undesirable cavitation, choking and shock waves in vessels with plaque and / or boundary-layer blockage (peak at winter). Cavitation is quite noisy and can be sufficiently violent to physically damage valves and blood vessels. Memory effects and transient pressure-spikes due to shock waves developed over the years in the choked blood-vessels create its walls stiffer and prone to rupture in the subsequent strokes." @default.
- W4246275163 created "2022-05-12" @default.
- W4246275163 creator A5039309774 @default.
- W4246275163 date "2020-02-05" @default.
- W4246275163 modified "2023-09-30" @default.
- W4246275163 title "Critical Blood Pressure Ratio and Memory Effects are Risk Factors for Stroke - Discovery of Biofluid Choking a Paradigm Shift in the Diagnostics Sciences of Hemorrhage and Ischaemic Heart Disease" @default.
- W4246275163 doi "https://doi.org/10.31219/osf.io/t67jv" @default.
- W4246275163 hasPublicationYear "2020" @default.
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