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- W4246337718 abstract "Abstract The preparation of native S‐palmitoylated (S‐palm) membrane proteins is one of the unsolved challenges in chemical protein synthesis. Herein, we report the first chemical synthesis of S‐palm membrane proteins by removable‐backbone‐modification‐assisted Ser/Thr ligation (RBM GABA ‐assisted STL). This method involves two critical steps: 1) synthesis of S‐palm peptides by a new γ‐aminobutyric acid based RBM (RBM GABA ) strategy, and 2) ligation of the S‐palm RBM‐modified peptides to give the desired S‐palm product by the STL method. The utility of the RBM GABA ‐assisted STL method was demonstrated by the synthesis of rabbit S‐palm sarcolipin (SLN) and S‐palm matrix‐2 (M2) ion channel. The synthesis of S‐palm membrane proteins highlights the importance of developing non‐NCL methods for chemical protein synthesis." @default.
- W4246337718 created "2022-05-12" @default.
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- W4246337718 creator A5053945912 @default.
- W4246337718 date "2020-02-12" @default.
- W4246337718 modified "2023-10-10" @default.
- W4246337718 title "Chemical Synthesis of Native S‐Palmitoylated Membrane Proteins through Removable‐Backbone‐Modification‐Assisted Ser/Thr Ligation" @default.
- W4246337718 cites W1600408851 @default.
- W4246337718 cites W1969429503 @default.
- W4246337718 cites W1977045919 @default.
- W4246337718 cites W1983612210 @default.
- W4246337718 cites W1986827801 @default.
- W4246337718 cites W2009457989 @default.
- W4246337718 cites W2017407373 @default.
- W4246337718 cites W2020979281 @default.
- W4246337718 cites W2021293377 @default.
- W4246337718 cites W2024316720 @default.
- W4246337718 cites W2025686590 @default.
- W4246337718 cites W2046771956 @default.
- W4246337718 cites W2052859437 @default.
- W4246337718 cites W2065656177 @default.
- W4246337718 cites W2071160031 @default.
- W4246337718 cites W2079657934 @default.
- W4246337718 cites W2082276184 @default.
- W4246337718 cites W2085873683 @default.
- W4246337718 cites W2086793679 @default.
- W4246337718 cites W2101369857 @default.
- W4246337718 cites W2103504451 @default.
- W4246337718 cites W2108396303 @default.
- W4246337718 cites W2113882468 @default.
- W4246337718 cites W2116179149 @default.
- W4246337718 cites W2126044089 @default.
- W4246337718 cites W2145537234 @default.
- W4246337718 cites W2150734705 @default.
- W4246337718 cites W2155574385 @default.
- W4246337718 cites W2159925468 @default.
- W4246337718 cites W2163061940 @default.
- W4246337718 cites W2163240400 @default.
- W4246337718 cites W2179281648 @default.
- W4246337718 cites W2288994088 @default.
- W4246337718 cites W2321622683 @default.
- W4246337718 cites W2331724405 @default.
- W4246337718 cites W2339078080 @default.
- W4246337718 cites W2340625992 @default.
- W4246337718 cites W2404881798 @default.
- W4246337718 cites W2418414723 @default.
- W4246337718 cites W2489045778 @default.
- W4246337718 cites W2493385008 @default.
- W4246337718 cites W2511719463 @default.
- W4246337718 cites W2520543091 @default.
- W4246337718 cites W2547459865 @default.
- W4246337718 cites W2549799008 @default.
- W4246337718 cites W2566797372 @default.
- W4246337718 cites W2594006964 @default.
- W4246337718 cites W2604210161 @default.
- W4246337718 cites W2750538904 @default.
- W4246337718 cites W2751331717 @default.
- W4246337718 cites W2751492513 @default.
- W4246337718 cites W2768881027 @default.
- W4246337718 cites W2769376007 @default.
- W4246337718 cites W2782354676 @default.
- W4246337718 cites W2783148619 @default.
- W4246337718 cites W2794497754 @default.
- W4246337718 cites W2798222701 @default.
- W4246337718 cites W2806826548 @default.
- W4246337718 cites W2818271651 @default.
- W4246337718 cites W2828038444 @default.
- W4246337718 cites W2897228524 @default.
- W4246337718 cites W2899092658 @default.
- W4246337718 cites W2901951468 @default.
- W4246337718 cites W2903087367 @default.
- W4246337718 cites W2903178638 @default.
- W4246337718 cites W2923939395 @default.
- W4246337718 cites W2947886265 @default.
- W4246337718 cites W2950842649 @default.
- W4246337718 cites W2955465948 @default.
- W4246337718 cites W2969807776 @default.
- W4246337718 cites W4213262935 @default.
- W4246337718 cites W4214949900 @default.
- W4246337718 cites W4229628765 @default.
- W4246337718 cites W4230601151 @default.
- W4246337718 cites W4236199208 @default.
- W4246337718 cites W4240286553 @default.
- W4246337718 cites W4240289211 @default.
- W4246337718 cites W4242490106 @default.
- W4246337718 cites W4245854257 @default.
- W4246337718 cites W4246169448 @default.