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- W4246367268 abstract "The dissolution behaviour in water of phenytoin in solid dispersions with urea, PEG and PVP have been studied in comparison with the corresponding physical mixtures and pure phenytoin. The results revealed a marked increase of dissolution rate and solubility of phenytoin contained in solid dispersion. An X-ray diffraction technique was employed to investigate the nature of the studied forms. Phenytoin was stable and did not decompose during preparation of the dispersion systems or during direct compression of the tablets. Dissolution rate was generally unchanged with age for most studied tablets." @default.
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- W4246367268 date "1987-02-01" @default.
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- W4246367268 title "Dissolution rates of partially water-soluble drugs from solid dispersion systems. II. Phenytoin" @default.
- W4246367268 doi "https://doi.org/10.1016/0378-5173(87)90068-8" @default.
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