Matches in SemOpenAlex for { <https://semopenalex.org/work/W4246437629> ?p ?o ?g. }
Showing items 1 to 67 of
67
with 100 items per page.
- W4246437629 abstract "Abstract Background: Diarrhoea, although easily curable, is a global cause of death for a half million children every year. Rotavirus and Campylobacter are the most common etiological agents of diarrhoea in children less than 5 years of age. However, in Nepal, these causative agents are not routinely examined for the diagnosis and treatment. The main objective of this study was to determine Campylobacter co-infection associated with rotavirus diarrhoea in children less than 5 years of age. Methods: A cross-sectional study was conducted at Kanti Children's Hospital (KCH), Kathmandu, Nepal from November 2017 to April 2018. A total of 303 stool specimens from children affected with diarrhoea were processed to detect rotavirus using a rapid rotavirus antigen detection test kit, and Campylobacter by microscopy, culture and biochemical tests. Antibiotic susceptibility tests of Campylobacter isolates were performed according to European Committee on Antimicrobial Susceptibility Testing (EUCAST) guidelines 2015. Results: Of 303 samples, 91 (30.0%) were positive for co-infection with rotavirus and Campylobacter . Rotavirus mono-infection was detected in 61 (20.1%), and Campylobacter mono-infection was detected in 81 (26.7%) samples. Patient’s age, month of infection, untreated water and frequent soil contact were the major risk factors for infections. Clinical features such as >9 loose motions per day, fever, vomiting, mild to moderate dehydration, diarrhea persisting 6-9 days and presence of mucus in stool were significant (p<0.05) clinical features, and were more severe in coinfection compared to mono-infections in multivariate analysis. Conclusion: The study shows a high rate of rotavirus and Campylobacter coinfection in children with diarrhoea. Diagnosis based management of diarrhoeal cases can guide the specific treatment. Keywords : Campylobacter , rotavirus, co-infection, diarrhoea, children" @default.
- W4246437629 created "2022-05-12" @default.
- W4246437629 creator A5027824726 @default.
- W4246437629 creator A5031908226 @default.
- W4246437629 creator A5069912863 @default.
- W4246437629 creator A5088899204 @default.
- W4246437629 date "2020-02-06" @default.
- W4246437629 modified "2023-09-24" @default.
- W4246437629 title "Co-infection with Campylobacter and rotavirus in less than 5 year old children with acute gastroenteritis in Nepal during 2017-2018" @default.
- W4246437629 doi "https://doi.org/10.21203/rs.2.13512/v3" @default.
- W4246437629 hasPublicationYear "2020" @default.
- W4246437629 type Work @default.
- W4246437629 citedByCount "0" @default.
- W4246437629 crossrefType "posted-content" @default.
- W4246437629 hasAuthorship W4246437629A5027824726 @default.
- W4246437629 hasAuthorship W4246437629A5031908226 @default.
- W4246437629 hasAuthorship W4246437629A5069912863 @default.
- W4246437629 hasAuthorship W4246437629A5088899204 @default.
- W4246437629 hasBestOaLocation W42464376291 @default.
- W4246437629 hasConcept C126322002 @default.
- W4246437629 hasConcept C137627325 @default.
- W4246437629 hasConcept C203014093 @default.
- W4246437629 hasConcept C2522874641 @default.
- W4246437629 hasConcept C2777813720 @default.
- W4246437629 hasConcept C2779802037 @default.
- W4246437629 hasConcept C2779910956 @default.
- W4246437629 hasConcept C2780852908 @default.
- W4246437629 hasConcept C2781367151 @default.
- W4246437629 hasConcept C501593827 @default.
- W4246437629 hasConcept C523546767 @default.
- W4246437629 hasConcept C54355233 @default.
- W4246437629 hasConcept C71924100 @default.
- W4246437629 hasConcept C86803240 @default.
- W4246437629 hasConcept C89423630 @default.
- W4246437629 hasConceptScore W4246437629C126322002 @default.
- W4246437629 hasConceptScore W4246437629C137627325 @default.
- W4246437629 hasConceptScore W4246437629C203014093 @default.
- W4246437629 hasConceptScore W4246437629C2522874641 @default.
- W4246437629 hasConceptScore W4246437629C2777813720 @default.
- W4246437629 hasConceptScore W4246437629C2779802037 @default.
- W4246437629 hasConceptScore W4246437629C2779910956 @default.
- W4246437629 hasConceptScore W4246437629C2780852908 @default.
- W4246437629 hasConceptScore W4246437629C2781367151 @default.
- W4246437629 hasConceptScore W4246437629C501593827 @default.
- W4246437629 hasConceptScore W4246437629C523546767 @default.
- W4246437629 hasConceptScore W4246437629C54355233 @default.
- W4246437629 hasConceptScore W4246437629C71924100 @default.
- W4246437629 hasConceptScore W4246437629C86803240 @default.
- W4246437629 hasConceptScore W4246437629C89423630 @default.
- W4246437629 hasLocation W42464376291 @default.
- W4246437629 hasLocation W42464376292 @default.
- W4246437629 hasLocation W42464376293 @default.
- W4246437629 hasOpenAccess W4246437629 @default.
- W4246437629 hasPrimaryLocation W42464376291 @default.
- W4246437629 hasRelatedWork W10411849 @default.
- W4246437629 hasRelatedWork W11272766 @default.
- W4246437629 hasRelatedWork W14180436 @default.
- W4246437629 hasRelatedWork W2039193 @default.
- W4246437629 hasRelatedWork W20662272 @default.
- W4246437629 hasRelatedWork W2229246 @default.
- W4246437629 hasRelatedWork W2534055 @default.
- W4246437629 hasRelatedWork W4886515 @default.
- W4246437629 hasRelatedWork W5302758 @default.
- W4246437629 hasRelatedWork W862221 @default.
- W4246437629 isParatext "false" @default.
- W4246437629 isRetracted "false" @default.
- W4246437629 workType "article" @default.