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- W4246458399 abstract "CEDM is a new advanced application of digital mammography using the intravenous injection of an iodinated contrast agent in conjunction with a mammography examination. Two basic CEDM techniques are under development: temporal subtraction and dual-energy techniques. Temporal subtraction CEDM imaging produces high-energy digital mammography images and subtraction of precontrast from the postcontrast images. Dual-energy subtraction imaging exploits the energy dependence of X-ray attenuation through materials of different compositions in the breast, specifi-cally iodine and soft tissues. A pair of low- and high-energy images is obtained after contrast and then the two images are combined to enhance areas of contrast uptake. This new breast imaging method can be easily implemented clinically using a current digital mammography system with minor adaptations and commercially available iodinated contrast agent. Initial clinical experience has shown the ability of CEDM to map the distribution of neovasculature induced by cancer using mammography. CEDM has been shown to improve the probability of malignancy and the BIRADS assessment when compared with the conventional mammography alone. The potential clinical applications are the determination of the extent of disease, the assessment of recurrent disease, the clarification of mammographically equivocal lesions, the detection of occult lesions on standard mammography, particularly in dense breast, and the monitoring of the response to chemotherapy. CEDM should be a useful adjunct to diagnostic mammography and a promising problem-solving and a staging tool." @default.
- W4246458399 created "2022-05-12" @default.
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- W4246458399 date "2010-01-01" @default.
- W4246458399 modified "2023-10-16" @default.
- W4246458399 title "Contrast-Enhanced Digital Mammography" @default.
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- W4246458399 doi "https://doi.org/10.1007/978-3-540-78450-0_12" @default.
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