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- W4246560003 abstract "Abstract Objectives: To assess risk factors associated with Clostridium difficile diarrhea in hospitalized adult patients, and to test the hypothesis that sucralfate ingestion is associated with nondetection of C difficile cytotoxin in stool specimens. Design: A retrospective case-control study of hospitalized adult patients who had stool specimens assayed for C difficile cytotoxin. For each patient who had positive C difficile cytotoxin, a patient who had negative C difficile cytotoxin was used as a control. The study period was January to December 1993. Setting: A community teaching hospital affiliated with a medical school in northeastern Ohio. Results: There were 91 case patients and 91 control patients. Cephalosporin exposure was identified as a risk factor in patients with C difficile diarrhea. The number of patients who had sucralfate ingestion was comparable in both groups of patients. Conclusions: Administration of cephalosporins was identified as a risk factor in patients with C difficile diar-rhea. We were not able to confirm a recent report of the association between ingestion of sucralfate and nondetection of C difficile cytotoxin in stool specimens. Our findings suggest that sucralfate ingestion is not associated with nondetection of C difficile cytotoxin in stool specimens. Assay of C difficile cytotoxin in stool specimens remains a valid method of diagnosing C difficile diarrhea, even in patients who ingest sucralfate." @default.
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- W4246560003 title "Risk Factors Associated With<i>Clostridium difficile</i>Diarrhea in Hospitalized Adult Patients: A Case-Control Study—Sucralfate Ingestion is Not a Negative Risk Factor" @default.
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- W4246560003 doi "https://doi.org/10.1017/s0195941700003817" @default.
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