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- W4246724105 abstract "The neurotoxicity of vincristine sulfate, a commonly used antineoplastic agent, has been well described. A literature review failed to reveal any absolute contraindications to the initial use of vincristine. We describe two patients with nodular sclerosing Hodgkin's disease in whom a rapidly progressive, but reversible, severe polyneuropathy developed when they were given a total of 4 mg of vincristine sulfate. Each was later shown to have the demyelinating form of Charcot-Marie-Tooth syndrome. This association suggests that the use of vincristine is contraindicated in patients with the demyelinating form of Charcot-Marie-Tooth syndrome. (<i>JAMA</i>1984;252:2862-2863)" @default.
- W4246724105 created "2022-05-12" @default.
- W4246724105 creator A5009831987 @default.
- W4246724105 date "1984-11-23" @default.
- W4246724105 modified "2023-09-24" @default.
- W4246724105 title "Polyneuropathy following vincristine therapy in two patients with Charcot-Marie-Tooth syndrome" @default.
- W4246724105 doi "https://doi.org/10.1001/jama.252.20.2862" @default.
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