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- W4246739334 abstract "This chapter presents an easy-to-follow algorithm for obstetric management of patients with diabetic ketoacidosis (DKA). DKA results from a relative or absolute deficiency of circulating insulin in the setting of excessive glucose counterregulatory hormones such as catecholamines, growth hormone, cortisol, and glucagon. Diabetic ketoacidosis develops in 2-10% of all pregnancies complicated by pregestational diabetes. It is extremely rare in gestational diabetes (<<1%), and effectively absent in nondiabetic women. Risk factors for the development of DKA include undiagnosed pregestational diabetes, pregnancy, emesis, noncompliance, infection, ß-agonist therapy, and antepartum corticosteroid therapy. Diabetic ketoacidosis is associated with a high maternal and perinatal mortality. The half-life of IV insulin is 2–4 min. DKA can recur in the absence of exogenous insulin. Subcutaneous insulin should therefore be restarted once the patient is eating. If the acidosis persists despite initial treatment, consider inadequate insulin administration, sepsis, or hypophosphatemia." @default.
- W4246739334 created "2022-05-12" @default.
- W4246739334 date "2016-10-21" @default.
- W4246739334 modified "2023-10-17" @default.
- W4246739334 title "Diabetic Ketoacidosis <sup>1</sup>" @default.
- W4246739334 doi "https://doi.org/10.1002/9781118849897.ch79" @default.
- W4246739334 hasPublicationYear "2016" @default.
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