Matches in SemOpenAlex for { <https://semopenalex.org/work/W4246806407> ?p ?o ?g. }
Showing items 1 to 68 of
68
with 100 items per page.
- W4246806407 endingPage "598" @default.
- W4246806407 startingPage "598" @default.
- W4246806407 abstract "A 47-year-old anicteric patient with plasma cell myeloma was noted to have 9660 mg/dL of monoclonal immunoglobulin G in her serum. More than 90% of her bone marrow cellularity was composed of sheets of atypical, nucleated, and multinucleate plasma cells. Her peripheral blood smear showed red blood cell rouleaux formation (Figure), which prohibited the accurate automated measurement of her red blood cell indices and interfered with her blood group determination and cross-matching in polyethylene glycol before blood transfusion. The high concentration of paraprotein also resulted in a noticeably homogeneous basophilic stained background of her peripheral blood smear, readily demonstrated after making a scratch on the slide and comparing the abnormally stained proteinaceous material to the clean colorless background of the slide. The increased blue coloration of the blood film was also observed on gross examination of the stained glass slide. This phenomenon is not pathognomonic of plasma cell myeloma but indicates a hypergammaglobulinemia that may be due to either a paraprotein or reactive increase in immunoglobulins.1–3 In some cases, this appearance can interfere with an assessment of morphologic detail. To prepare films free of this artifact, it may be necessary to dilute the blood sample in isotonic saline.2 The M-protein in this case also resulted in pseudohyponatremia and an artefactually elevated total bilirubin level (18.6 mg/dL [318 ;gmmol/L]). Although paraproteins may commonly interfere with automated blood cell counts4 and electrolyte measurements,5 their interference with total bilirubin is the result of an unusual idiosyncratic reaction between the M-protein and the specific analytic method used.6 As occurred in this case, spurious hyperbilirubinemia from paraprotein interference may cause clinical confusion." @default.
- W4246806407 created "2022-05-12" @default.
- W4246806407 creator A5028342220 @default.
- W4246806407 creator A5057607483 @default.
- W4246806407 creator A5059068809 @default.
- W4246806407 creator A5085524673 @default.
- W4246806407 date "2004-05-01" @default.
- W4246806407 modified "2023-09-23" @default.
- W4246806407 title "The Scratch Test" @default.
- W4246806407 cites W1983454059 @default.
- W4246806407 cites W2099482744 @default.
- W4246806407 cites W2408299113 @default.
- W4246806407 doi "https://doi.org/10.5858/2004-128-598-tst" @default.
- W4246806407 hasPublicationYear "2004" @default.
- W4246806407 type Work @default.
- W4246806407 citedByCount "1" @default.
- W4246806407 countsByYear W42468064072021 @default.
- W4246806407 crossrefType "journal-article" @default.
- W4246806407 hasAuthorship W4246806407A5028342220 @default.
- W4246806407 hasAuthorship W4246806407A5057607483 @default.
- W4246806407 hasAuthorship W4246806407A5059068809 @default.
- W4246806407 hasAuthorship W4246806407A5085524673 @default.
- W4246806407 hasConcept C126322002 @default.
- W4246806407 hasConcept C142724271 @default.
- W4246806407 hasConcept C152669594 @default.
- W4246806407 hasConcept C159654299 @default.
- W4246806407 hasConcept C170094789 @default.
- W4246806407 hasConcept C185592680 @default.
- W4246806407 hasConcept C203014093 @default.
- W4246806407 hasConcept C2776396001 @default.
- W4246806407 hasConcept C2776557347 @default.
- W4246806407 hasConcept C2780007613 @default.
- W4246806407 hasConcept C2908937092 @default.
- W4246806407 hasConcept C45189115 @default.
- W4246806407 hasConcept C71924100 @default.
- W4246806407 hasConceptScore W4246806407C126322002 @default.
- W4246806407 hasConceptScore W4246806407C142724271 @default.
- W4246806407 hasConceptScore W4246806407C152669594 @default.
- W4246806407 hasConceptScore W4246806407C159654299 @default.
- W4246806407 hasConceptScore W4246806407C170094789 @default.
- W4246806407 hasConceptScore W4246806407C185592680 @default.
- W4246806407 hasConceptScore W4246806407C203014093 @default.
- W4246806407 hasConceptScore W4246806407C2776396001 @default.
- W4246806407 hasConceptScore W4246806407C2776557347 @default.
- W4246806407 hasConceptScore W4246806407C2780007613 @default.
- W4246806407 hasConceptScore W4246806407C2908937092 @default.
- W4246806407 hasConceptScore W4246806407C45189115 @default.
- W4246806407 hasConceptScore W4246806407C71924100 @default.
- W4246806407 hasIssue "5" @default.
- W4246806407 hasLocation W42468064071 @default.
- W4246806407 hasOpenAccess W4246806407 @default.
- W4246806407 hasPrimaryLocation W42468064071 @default.
- W4246806407 hasRelatedWork W1489191753 @default.
- W4246806407 hasRelatedWork W187289315 @default.
- W4246806407 hasRelatedWork W1970707390 @default.
- W4246806407 hasRelatedWork W1972137073 @default.
- W4246806407 hasRelatedWork W2005843898 @default.
- W4246806407 hasRelatedWork W2010348528 @default.
- W4246806407 hasRelatedWork W2118468335 @default.
- W4246806407 hasRelatedWork W2281967836 @default.
- W4246806407 hasRelatedWork W2321288317 @default.
- W4246806407 hasRelatedWork W4290134541 @default.
- W4246806407 hasVolume "128" @default.
- W4246806407 isParatext "false" @default.
- W4246806407 isRetracted "false" @default.
- W4246806407 workType "article" @default.