Matches in SemOpenAlex for { <https://semopenalex.org/work/W4246917029> ?p ?o ?g. }
Showing items 1 to 67 of
67
with 100 items per page.
- W4246917029 endingPage "661" @default.
- W4246917029 startingPage "656" @default.
- W4246917029 abstract "Rapid progress in oligonucleotide therapeutics has continued over the past year as major programs established in the past four years have grown and begun to be productive. Important advances were reported in the medicinal chemistry of oligonucleotides and in understanding their pharmacodynamic properties. Significant progress was made in understanding the pharmacokinetic and toxicologic properties of first generation analogs, particularly phosphorothioates and one oligonucleotide, ISIS 2105, entered clinical trials. Additionally, combinatorial approaches designed to identify oligonucleotides that may bind to a variety of targets were reported." @default.
- W4246917029 created "2022-05-12" @default.
- W4246917029 creator A5077755519 @default.
- W4246917029 date "1992-12-01" @default.
- W4246917029 modified "2023-09-30" @default.
- W4246917029 title "Oligonucleotide therapy" @default.
- W4246917029 cites W1591140747 @default.
- W4246917029 cites W1614066667 @default.
- W4246917029 cites W1752221293 @default.
- W4246917029 cites W1964858690 @default.
- W4246917029 cites W1989051098 @default.
- W4246917029 cites W2004059420 @default.
- W4246917029 cites W2019818589 @default.
- W4246917029 cites W2035164099 @default.
- W4246917029 cites W2040231751 @default.
- W4246917029 cites W2061419481 @default.
- W4246917029 cites W2169149151 @default.
- W4246917029 cites W2229138924 @default.
- W4246917029 cites W2949099520 @default.
- W4246917029 cites W3026227968 @default.
- W4246917029 cites W4240431031 @default.
- W4246917029 cites W4245743410 @default.
- W4246917029 doi "https://doi.org/10.1016/0958-1669(92)90012-8" @default.
- W4246917029 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1369122" @default.
- W4246917029 hasPublicationYear "1992" @default.
- W4246917029 type Work @default.
- W4246917029 citedByCount "19" @default.
- W4246917029 countsByYear W42469170292012 @default.
- W4246917029 crossrefType "journal-article" @default.
- W4246917029 hasAuthorship W4246917029A5077755519 @default.
- W4246917029 hasConcept C129312508 @default.
- W4246917029 hasConcept C185592680 @default.
- W4246917029 hasConcept C552990157 @default.
- W4246917029 hasConcept C55493867 @default.
- W4246917029 hasConcept C70721500 @default.
- W4246917029 hasConcept C71924100 @default.
- W4246917029 hasConcept C86803240 @default.
- W4246917029 hasConcept C98274493 @default.
- W4246917029 hasConceptScore W4246917029C129312508 @default.
- W4246917029 hasConceptScore W4246917029C185592680 @default.
- W4246917029 hasConceptScore W4246917029C552990157 @default.
- W4246917029 hasConceptScore W4246917029C55493867 @default.
- W4246917029 hasConceptScore W4246917029C70721500 @default.
- W4246917029 hasConceptScore W4246917029C71924100 @default.
- W4246917029 hasConceptScore W4246917029C86803240 @default.
- W4246917029 hasConceptScore W4246917029C98274493 @default.
- W4246917029 hasIssue "6" @default.
- W4246917029 hasLocation W42469170291 @default.
- W4246917029 hasLocation W42469170292 @default.
- W4246917029 hasOpenAccess W4246917029 @default.
- W4246917029 hasPrimaryLocation W42469170291 @default.
- W4246917029 hasRelatedWork W1533184902 @default.
- W4246917029 hasRelatedWork W2068164457 @default.
- W4246917029 hasRelatedWork W2076712430 @default.
- W4246917029 hasRelatedWork W2101090140 @default.
- W4246917029 hasRelatedWork W2439422421 @default.
- W4246917029 hasRelatedWork W2748952813 @default.
- W4246917029 hasRelatedWork W2763910338 @default.
- W4246917029 hasRelatedWork W2899084033 @default.
- W4246917029 hasRelatedWork W2411539162 @default.
- W4246917029 hasRelatedWork W2992156405 @default.
- W4246917029 hasVolume "3" @default.
- W4246917029 isParatext "false" @default.
- W4246917029 isRetracted "false" @default.
- W4246917029 workType "article" @default.