Matches in SemOpenAlex for { <https://semopenalex.org/work/W4246918678> ?p ?o ?g. }
Showing items 1 to 63 of
63
with 100 items per page.
- W4246918678 endingPage "2" @default.
- W4246918678 startingPage "2" @default.
- W4246918678 abstract "Glycolipids and glycoproteins have long been of interest to neuroscientists in view of their critical involvement in disorders affecting the nervous system. Current investigations are focused on the elucidation of specific biological functions of these molecules and on the role that failure to carry out normal function has on neurophysiology. These include physiological roles in cell-cell and intracellular signaling, including glycosphingolipid-cholesterol ‘lipid rafts’; sphingosine, sphingosine phosphate and ceramide phosphate intracellular messengers exerting a variety of effects on cell proliferation and neural differentiation; neural development; modulatory agents for a variety of membrane enzymes, receptors, ion channels and adhesion factors; neurotrophic factor modulated cell survival and apoptosis; and cell adhesion. A number of technical and conceptual advances have made this a particularly active forefront area of research. For example, there is an on-going development of databases from lipidomics and glycomics; an important integration with molecular biology is underway, with many of the genes for lipid and carbohydrate processing/synthesizing enzymes having been cloned and many genetically modified mice developed; significant advances are being made in optical methods to identify and visualize, often in real time, the intracellular movements of glycolipid structures; these and other approaches are being increasingly applied to the direct analysis of human neural disease, such as Alzheimer’s Disease and demyelination. Together, these efforts offer tremendous promise for enhanced prevention, diagnosis and treatment of neural diseases. The research papers in this Special Issue are derived from some of the presentations from a three-day symposium, the Second ISN Special Neurochemistry Conference on ‘Neural Glycoproteins and Glycolipids’. The gathering was held on the lovely Caribbean island of Antigua, December 1–5, 2006 (Chair, Steve Pfeiffer, USA; Co-chairs Tony Futerman, Israel and Kuni Suzuki, Japan) with the aid of colleagues at the American University of Antigua (AUA) Medical School who ably acted as local hosts (Surendra Parmar, Reza Sunii, Majid Pathan, Steve Glasser, and ISN/AUA liaison Rashmi Bansal). The meeting abstracts have been published in the Journal of Neurochemistry, volume 99, Supplement 1. The current forefronts of the field were investigated through major addresses on key aspects of this burgeoning field of inquiry, supplemented by additional, shorter talks by young investigators, and bolstered further by particularly vigorous poster sessions. Approximately 120 scientists were in attendance from 15 countries. Key areas of concentration included Moderns Methods of Analysis and Integration; Bioinformatics; Genetic Models; Cellular Migration and Early Neural Development, and Cellular Differentiation; Synthesis, Trafficking and Sorting of Lipids and Glycoproteins; Intracellular Signaling; Glycosphingolipids and Microdomains; Adhesion and Recognition; Cell-Cell Communication; Lipid-Protein Interactions; Relationship to Neural Disease. The meeting was by all standards a resounding success due to the enthusiasm and participation of the attendees." @default.
- W4246918678 created "2022-05-12" @default.
- W4246918678 creator A5027472835 @default.
- W4246918678 creator A5067203212 @default.
- W4246918678 date "2007-11-01" @default.
- W4246918678 modified "2023-09-23" @default.
- W4246918678 title "Preface" @default.
- W4246918678 doi "https://doi.org/10.1111/j.1471-4159.2007.04821.x" @default.
- W4246918678 hasPublicationYear "2007" @default.
- W4246918678 type Work @default.
- W4246918678 citedByCount "1" @default.
- W4246918678 countsByYear W42469186782016 @default.
- W4246918678 crossrefType "journal-article" @default.
- W4246918678 hasAuthorship W4246918678A5027472835 @default.
- W4246918678 hasAuthorship W4246918678A5067203212 @default.
- W4246918678 hasConcept C104317684 @default.
- W4246918678 hasConcept C106686826 @default.
- W4246918678 hasConcept C163235415 @default.
- W4246918678 hasConcept C169760540 @default.
- W4246918678 hasConcept C190283241 @default.
- W4246918678 hasConcept C2776931407 @default.
- W4246918678 hasConcept C2777851122 @default.
- W4246918678 hasConcept C46111723 @default.
- W4246918678 hasConcept C55493867 @default.
- W4246918678 hasConcept C62478195 @default.
- W4246918678 hasConcept C79266657 @default.
- W4246918678 hasConcept C79879829 @default.
- W4246918678 hasConcept C86803240 @default.
- W4246918678 hasConcept C95444343 @default.
- W4246918678 hasConceptScore W4246918678C104317684 @default.
- W4246918678 hasConceptScore W4246918678C106686826 @default.
- W4246918678 hasConceptScore W4246918678C163235415 @default.
- W4246918678 hasConceptScore W4246918678C169760540 @default.
- W4246918678 hasConceptScore W4246918678C190283241 @default.
- W4246918678 hasConceptScore W4246918678C2776931407 @default.
- W4246918678 hasConceptScore W4246918678C2777851122 @default.
- W4246918678 hasConceptScore W4246918678C46111723 @default.
- W4246918678 hasConceptScore W4246918678C55493867 @default.
- W4246918678 hasConceptScore W4246918678C62478195 @default.
- W4246918678 hasConceptScore W4246918678C79266657 @default.
- W4246918678 hasConceptScore W4246918678C79879829 @default.
- W4246918678 hasConceptScore W4246918678C86803240 @default.
- W4246918678 hasConceptScore W4246918678C95444343 @default.
- W4246918678 hasIssue "s1" @default.
- W4246918678 hasLocation W42469186781 @default.
- W4246918678 hasOpenAccess W4246918678 @default.
- W4246918678 hasPrimaryLocation W42469186781 @default.
- W4246918678 hasRelatedWork W2012509070 @default.
- W4246918678 hasRelatedWork W2028303810 @default.
- W4246918678 hasRelatedWork W2036429256 @default.
- W4246918678 hasRelatedWork W2084119956 @default.
- W4246918678 hasRelatedWork W2093676869 @default.
- W4246918678 hasRelatedWork W2118560029 @default.
- W4246918678 hasRelatedWork W2136238444 @default.
- W4246918678 hasRelatedWork W2169979796 @default.
- W4246918678 hasRelatedWork W2357441804 @default.
- W4246918678 hasRelatedWork W4205676635 @default.
- W4246918678 hasVolume "103" @default.
- W4246918678 isParatext "false" @default.
- W4246918678 isRetracted "false" @default.
- W4246918678 workType "article" @default.