Matches in SemOpenAlex for { <https://semopenalex.org/work/W4246962000> ?p ?o ?g. }
Showing items 1 to 78 of
78
with 100 items per page.
- W4246962000 endingPage "413" @default.
- W4246962000 startingPage "405" @default.
- W4246962000 abstract "Objective: Given the high mortality and prolonged duration of mechanical ventilation of COVID-19 patients, we evaluated the safety and efficacy of hyperbaric oxygen for COVID-19 patients with respiratory distress. Methods: This is a single-center clinical trial of COVID-19 patients at NYU Winthrop Hospital from March 31 to April 28, 2020. Patients in this trial received hyperbaric oxygen therapy at 2.0 atmospheres of pressure in monoplace hyperbaric chambers for 90 minutes daily for a maximum of five total treatments. Controls were identified using propensity score matching among COVID-19 patients admitted during the same time period. Using competing-risks survival regression, we analyzed our primary outcome of inpatient mortality and secondary outcome of mechanical ventilation. Results: We treated 20 COVID-19 patients with hyperbaric oxygen. Ages ranged from 30 to 79 years with an oxygen requirement ranging from 2 to 15 liters on hospital days 0 to 14. Of these 20 patients, two (10%) were intubated and died, and none remain hospitalized. Among 60 propensity-matched controls based on age, sex, body mass index, coronary artery disease, troponin, D-dimer, hospital day, and oxygen requirement, 18 (30%) were intubated, 13 (22%) have died, and three (5%) remain hospitalized (with one still requiring mechanical ventilation). Assuming no further deaths among controls, we estimate that the adjusted subdistribution hazard ratios were 0.37 for inpatient mortality (p=0.14) and 0.26 for mechanical ventilation (p=0.046). Conclusions: Though limited by its study design, our results demonstrate the safety of hyperbaric oxygen among COVID-19 patients and strongly suggests the need for a well-designed, multi-center randomized control trial." @default.
- W4246962000 created "2022-05-12" @default.
- W4246962000 creator A5012521199 @default.
- W4246962000 creator A5012621096 @default.
- W4246962000 creator A5014146114 @default.
- W4246962000 creator A5028090225 @default.
- W4246962000 creator A5031173656 @default.
- W4246962000 creator A5042581777 @default.
- W4246962000 creator A5042906630 @default.
- W4246962000 creator A5044628361 @default.
- W4246962000 creator A5046088363 @default.
- W4246962000 creator A5057093538 @default.
- W4246962000 creator A5058380201 @default.
- W4246962000 creator A5061032994 @default.
- W4246962000 creator A5073284312 @default.
- W4246962000 creator A5083541476 @default.
- W4246962000 date "2020-03-01" @default.
- W4246962000 modified "2023-09-29" @default.
- W4246962000 title "Hyperbaric oxygen therapy for COVID-19 patients with respiratory distress: treated cases versus propensity-matched controls" @default.
- W4246962000 doi "https://doi.org/10.22462/03.20.2020.1" @default.
- W4246962000 hasPublicationYear "2020" @default.
- W4246962000 type Work @default.
- W4246962000 citedByCount "3" @default.
- W4246962000 countsByYear W42469620002021 @default.
- W4246962000 countsByYear W42469620002022 @default.
- W4246962000 crossrefType "journal-article" @default.
- W4246962000 hasAuthorship W4246962000A5012521199 @default.
- W4246962000 hasAuthorship W4246962000A5012621096 @default.
- W4246962000 hasAuthorship W4246962000A5014146114 @default.
- W4246962000 hasAuthorship W4246962000A5028090225 @default.
- W4246962000 hasAuthorship W4246962000A5031173656 @default.
- W4246962000 hasAuthorship W4246962000A5042581777 @default.
- W4246962000 hasAuthorship W4246962000A5042906630 @default.
- W4246962000 hasAuthorship W4246962000A5044628361 @default.
- W4246962000 hasAuthorship W4246962000A5046088363 @default.
- W4246962000 hasAuthorship W4246962000A5057093538 @default.
- W4246962000 hasAuthorship W4246962000A5058380201 @default.
- W4246962000 hasAuthorship W4246962000A5061032994 @default.
- W4246962000 hasAuthorship W4246962000A5073284312 @default.
- W4246962000 hasAuthorship W4246962000A5083541476 @default.
- W4246962000 hasConcept C126322002 @default.
- W4246962000 hasConcept C141071460 @default.
- W4246962000 hasConcept C141983124 @default.
- W4246962000 hasConcept C17923572 @default.
- W4246962000 hasConcept C207103383 @default.
- W4246962000 hasConcept C2777080012 @default.
- W4246962000 hasConcept C2780630273 @default.
- W4246962000 hasConcept C42219234 @default.
- W4246962000 hasConcept C44249647 @default.
- W4246962000 hasConcept C71924100 @default.
- W4246962000 hasConceptScore W4246962000C126322002 @default.
- W4246962000 hasConceptScore W4246962000C141071460 @default.
- W4246962000 hasConceptScore W4246962000C141983124 @default.
- W4246962000 hasConceptScore W4246962000C17923572 @default.
- W4246962000 hasConceptScore W4246962000C207103383 @default.
- W4246962000 hasConceptScore W4246962000C2777080012 @default.
- W4246962000 hasConceptScore W4246962000C2780630273 @default.
- W4246962000 hasConceptScore W4246962000C42219234 @default.
- W4246962000 hasConceptScore W4246962000C44249647 @default.
- W4246962000 hasConceptScore W4246962000C71924100 @default.
- W4246962000 hasLocation W42469620001 @default.
- W4246962000 hasOpenAccess W4246962000 @default.
- W4246962000 hasPrimaryLocation W42469620001 @default.
- W4246962000 hasRelatedWork W2025908145 @default.
- W4246962000 hasRelatedWork W2354699621 @default.
- W4246962000 hasRelatedWork W2363264463 @default.
- W4246962000 hasRelatedWork W2368279359 @default.
- W4246962000 hasRelatedWork W2368511375 @default.
- W4246962000 hasRelatedWork W2379083533 @default.
- W4246962000 hasRelatedWork W2381854303 @default.
- W4246962000 hasRelatedWork W2883646890 @default.
- W4246962000 hasRelatedWork W2974702110 @default.
- W4246962000 hasRelatedWork W3181655116 @default.
- W4246962000 isParatext "false" @default.
- W4246962000 isRetracted "false" @default.
- W4246962000 workType "article" @default.