FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4247098689> ?p ?o ?g. }

• W4247098689 endingPage "1945" @default.
• W4247098689 startingPage "1944" @default.
• W4247098689 abstract "Early clinical experiences with extracorporeal membrane oxygenation (ECMO) failed as a consequence of irreversible end-organ disease rather than the technical limitations of keeping patients alive on ECMO [1Zapol W.M. Kitz R.J. Buying time with artificial lungs.New Engl J Med. 1972; 286: 657-658Crossref PubMed Scopus (19) Google Scholar]. The recent success of ECMO as a bridge to survival in patients with severe acute respiratory distress syndrome (ARDS) can be attributed largely to patient selection and ventilation management strategies to reduce ventilator associated lung injury [2Noah MA, Peek GJ, Finney SJ, et al. Referral to an extracorporeal membrane oxygenation center and mortality among patients with severe 2009 influenza A(H1N1). JAMA 011;306:1659–68.Google Scholar, 3Peek G.J. Mugford M. Tiruvoipati R. et al.Efficacy and economic assessment of conventional ventilatory support versus extracorporeal membrane oxygenation for severe adult respiratory failure (CESAR): a multicentre randomised controlled trial.Lancet. 2009; 374: 1351-1363Abstract Full Text Full Text PDF PubMed Scopus (2367) Google Scholar]. This improved understanding of the clinical applications of ECMO combined with advances in technology, including improved membrane oxygenators and pumps, improved cannulation strategies, reduced inflammation and cell trauma, decreased risk of thrombosis, and the selective use of venovenous ECMO to decrease the risk of arterial injury and stroke, has spurred renewed interest in ECMO as a salvage therapy. As a result, many centers are experiencing an increased demand for ECMO together with the number of patients in the intensive care unit being supported with ECMO. Data to help guide which patients would ultimately benefit from ECMO and which patients should be continued on ECMO once it has been implemented is important to refine the clinical application of this costly technology. The single-center study by Hsiao and colleagues [4Hsiao C-C. Chang C-H. Fan P-C. et al.Prognosis of patients with acute respiratory distress syndrome on extracorporeal membrane oxygenation: the impact of urine output on mortality.Ann Thorac Surg. 2014; 97: 1939-1945Google Scholar] reported that patients with ARDS on venovenous or venoarterial ECMO had higher mortality if the urine output was less than 1,432 mL in the first 24 hours after ECMO cannulation. Multivariate logistic regression also found that a mean arterial pressure less than 70 mm Hg, Apache II score greater than 30, and a platelet count less than 118 × 103 platelets/μL were independent risk factors for mortality after ECMO decannulation. The importance of oliguria over the first 24 hours is probably an early indicator of impending renal failure because increases in creatinine or blood urea nitrogen occur later. This finding adds support to the existing experience that irreversible organ dysfunction (eg, brain, liver, kidney) decreases the effectiveness of ECMO as a bridge to survival. Moreover, this finding suggests that the most effective application of ECMO is when it is initiated before significant organ dysfunction develops. The use of creatinine only as a measure of renal function in the APACHE II score might explain the improved predictive ability of urine output. It is also important to note that hypoxemia, mean arterial pressure, platelet count, and creatinine or urine output were variables for calculating the sequential organ failure assessment (SOFA) score, explaining why the SOFA score was not a significant predictor in the multivariate analysis. ECMO is a resource-intensive therapy that can increase chances for survival in ARDS, but can unnecessarily prolong death if used in patients with irreversible end-organ injury. This study provides information for selecting which patients would most benefit from this life-saving therapy. Prognosis of Patients With Acute Respiratory Distress Syndrome on Extracorporeal Membrane Oxygenation: the Impact of Urine Output on MortalityThe Annals of Thoracic SurgeryVol. 97Issue 6PreviewExtracorporeal membrane oxygenation (ECMO) has been utilized for patients in critical condition, including life-threatening respiratory failure and postcardiotomy cardiogenic shock. This study analyzed the outcomes of patients with acute respiratory distress syndrome (ARDS) treated by ECMO and identified the relationship between prognosis and urine output (UO) obtained on the first day of ECMO support. Full-Text PDF" @default.
• W4247098689 created "2022-05-12" @default.
• W4247098689 creator A5022167997 @default.
• W4247098689 creator A5057881453 @default.
• W4247098689 date "2014-06-01" @default.
• W4247098689 modified "2023-09-29" @default.
• W4247098689 title "Invited Commentary" @default.
• W4247098689 doi "https://doi.org/10.1016/j.athoracsur.2014.02.048" @default.
• W4247098689 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24882282" @default.
• W4247098689 hasPublicationYear "2014" @default.
• W4247098689 type Work @default.
• W4247098689 citedByCount "0" @default.
• W4247098689 crossrefType "journal-article" @default.
• W4247098689 hasAuthorship W4247098689A5022167997 @default.
• W4247098689 hasAuthorship W4247098689A5057881453 @default.
• W4247098689 hasConcept C126322002 @default.
• W4247098689 hasConcept C141071460 @default.
• W4247098689 hasConcept C177713679 @default.
• W4247098689 hasConcept C2776348555 @default.
• W4247098689 hasConcept C2776376669 @default.
• W4247098689 hasConcept C2776858399 @default.
• W4247098689 hasConcept C2776888751 @default.
• W4247098689 hasConcept C2777080012 @default.
• W4247098689 hasConcept C2777714996 @default.
• W4247098689 hasConcept C42219234 @default.
• W4247098689 hasConcept C71924100 @default.
• W4247098689 hasConceptScore W4247098689C126322002 @default.
• W4247098689 hasConceptScore W4247098689C141071460 @default.
• W4247098689 hasConceptScore W4247098689C177713679 @default.
• W4247098689 hasConceptScore W4247098689C2776348555 @default.
• W4247098689 hasConceptScore W4247098689C2776376669 @default.
• W4247098689 hasConceptScore W4247098689C2776858399 @default.
• W4247098689 hasConceptScore W4247098689C2776888751 @default.
• W4247098689 hasConceptScore W4247098689C2777080012 @default.
• W4247098689 hasConceptScore W4247098689C2777714996 @default.
• W4247098689 hasConceptScore W4247098689C42219234 @default.
• W4247098689 hasConceptScore W4247098689C71924100 @default.
• W4247098689 hasIssue "6" @default.
• W4247098689 hasLocation W42470986891 @default.
• W4247098689 hasLocation W42470986892 @default.
• W4247098689 hasOpenAccess W4247098689 @default.
• W4247098689 hasPrimaryLocation W42470986891 @default.
• W4247098689 hasRelatedWork W2068737793 @default.
• W4247098689 hasRelatedWork W2121172047 @default.
• W4247098689 hasRelatedWork W2149506185 @default.
• W4247098689 hasRelatedWork W2739819551 @default.
• W4247098689 hasRelatedWork W3023589795 @default.
• W4247098689 hasRelatedWork W3044332657 @default.
• W4247098689 hasRelatedWork W3117573775 @default.
• W4247098689 hasRelatedWork W3186200520 @default.
• W4247098689 hasRelatedWork W3186544290 @default.
• W4247098689 hasRelatedWork W4200392079 @default.
• W4247098689 hasVolume "97" @default.
• W4247098689 isParatext "false" @default.
• W4247098689 isRetracted "false" @default.
• W4247098689 workType "article" @default.