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• W4247166048 abstract "Background:There are no validated systems for measuring pain from osteoarthritis in cats. Hypothesis:Owner subjective assessments and an activity monitor (AM) can be used to detect pain in cats with osteoarthritis and to assess efficacy of treatments. Animals:Thirteen cats older than 10 years old, with owner-assessed decreases in activity, painful arthritic joints, and clinically normal blood work were included and evaluated for 3 weeks. Methods:A collar-mounted AM measured activity and a client-specific outcome measure (CSOM) questionnaire characterized the severity of impairment. Overall global quality of life was also evaluated for each treatment. In weeks 2 and 3, meloxicam (0.1 mg/kg, day 1; 0.05 mg/kg, days 2–5) or a placebo was administered in a blinded, randomized, cross-over manner to test the assessment systems. Results:The cats had a median of 4 arthritic appendicular joints. Activity counts for the week when cats (complete data on activity; n = 9) were administered meloxicam were significantly higher than at baseline (P= .02) but not after placebo (P= .06). Baseline activity counts were not significantly different from placebo (P= .6). The CSOM data (n = 13) showed that owners considered their cats to be more active on meloxicam compared with baseline (P= .001) and placebo (P < .004), and more active on placebo than at baseline (P < .01). Global quality of life improved significantly with meloxicam (P < .042). Conclusions and Clinical Importance: Both an AM and a CSOM system can detect behavior associated with pain relief in cats that are arthritic. Objective activity data might allow subjective assessment systems to be validated for use in clinical studies." @default.
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• W4247166048 date "2007-05-01" @default.
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• W4247166048 title "Evaluation of Client-Specific Outcome Measures and Activity Monitoring to Measure Pain Relief in Cats with Osteoarthritis" @default.
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• W4247166048 doi "https://doi.org/10.1111/j.1939-1676.2007.tb02983.x" @default.
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