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• W4247292289 abstract "Patent ductus arteriosus, a persistent communication between the descending thoracic aorta and the pulmonary artery, is one of the most common congenital heart defects. Transcatheter occlusion is an effective alternative to surgery and is currently standard of care for most patients. The authors present the results from a single center after twelve years of experience using this technique. Retrospective analysis of medical records from all patients referred to a tertiary center for percutaneous ductus closure between January 2006 and September 2018. A total of 221 patients were referred, with a mean age of 5.5 years-old (16 patients were infants, with the youngest aged four months). A Nit-Occlud® coil was used 139 times (62.9%), an Amplatzer™ duct occluder 79 times (35.7%), and vascular plugs were used three times. Percutaneous closure was achieved in every treated patient, with 1.4% maintaining residual shunting. Although higher overall coil device implantation was noted, duct occluder usage has been greater since 2011. Of all the coils, 55% were either 4x4 or 5x4 mm, and 73% of all Amplatzer duct occluders were either 6x4 or 8x6 mm, which correlates to the majority of patients having a small to moderately sized ductus. No complications were noted during the procedure, with a 1.8% post-procedure complication rate (one device embolization after 48 hours and three cases of loss of arterial pulse). Percutaneous patent ductus arteriosus closure was safe and effective in this setting, with a low global complication rate and similar outcomes to most equivalent centers. A persistência de canal arterial, uma comunicação entre a aorta descendente torácica e a artéria pulmonar, é uma das cardiopatias congénitas mais comuns. O encerramento percutâneo, uma alternativa eficaz à cirurgia, corresponde atualmente ao tratamento de eleição na maioria dos doentes. Os autores apresentam os resultados de um centro de referência após doze anos de experiência com esta técnica. Análise retrospetiva dos registos eletrónicos de todos os doentes orientados para encerramento percutâneo num centro de referência entre janeiro de 2006 e setembro de 2018. Foram referenciados 221 doentes, com média de 5,5 anos (16 lactentes, o mais novo com quatro meses de idade). Globalmente, 139 pacientes foram tratados com coil Nit-Occlud® (62.9%), 79 pacientes foram tratados com Amplatzer duct occluders (35,7%) e plugs vasculares foram utilizados três vezes. O encerramento percutâneo foi conseguido em todos os doentes tratados, com shunt residual em 1,4% dos casos. De todos os coils , 55% eram 4x4 ou 5x4 mm e 73% de todos os Amplatzer duct occluders eram 6x4 mm ou 8x6 mm, refletindo o facto de a maioria dos doentes apresentar canais arteriais de pequena-média dimensão. Não foram descritas complicações durante o procedimento, reportando-se uma taxa de complicações pós-procedimento de 1,8% (uma embolização de dispositivo após 48 horas e três casos de perda de pulso arterial). O encerramento percutâneo da persistência de canal arterial demonstrou ser seguro e eficaz neste contexto, com uma baixa taxa de complicações e resultados semelhantes a outros centros equivalentes." @default.
• W4247292289 created "2022-05-12" @default.
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• W4247292289 date "2021-08-01" @default.
• W4247292289 modified "2023-10-16" @default.
• W4247292289 title "Percutaneous patent ductus arteriosus closure: Twelve years of experience" @default.
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• W4247292289 doi "https://doi.org/10.1016/j.repc.2020.09.008" @default.
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