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- W4247443318 abstract "ObjectiveTo address patient safety and a source of major obstetrical morbidity, we initiated a comprehensive maternal hemorrhage protocol (HP). The objective of this study was to determine if the HP reduced the severity of OB hemorrhage, the number patients requiring transfusion or the number of units transfused.Study DesingThe key elements of the HP are: admission risk assessment, measurement of blood loss, early uterotonics use, early obstetrician and anesthesiologist presence, and activation of key ancillary hospital personnel. The severity of hemorrhage was based on a 3 stage system: Stage 1=bleeding greater than expected; Stage 2=bleeding not responding to conservative treatment; Stage 3=continued bleeding with actual or expected blood loss to exceed 1500 cc. At Stage 3, fixed ratios of blood products were immediately released (RBC, FFP, Cryo, Plts). Patients activated to each stage were prospectively collected 4 months prior to, and in three 4-month time periods post-HP. The total number of patients receiving blood products and the number of units transfused was compared during the 12-month time period prior to, and after, the HP was initiated. Data was analyzed by T-test and ANOVA.ResultsDuring the study period there were 5813 deliveries. The maternal hemorrhage rate (Stage 1-3) was 4.9%. Relative to pre-HP, fewer patients required Stage 2 intervention post-HP (53%→18%, P=0.02) and more patients were succesfully treated at Stage 1 (35%→82%, p=0.02). There was a trend towards a reduction of patients requiring Stage 3 intervention post-HP (p=0.08). Although the number of patients reaching Stage 3 was not significantly lower, the units of blood products transfused in the 12 months pre-HP was significantly higher than the 12 month Post-HP (16.7→ 6.3 units/month, p<0.01).ConclusionsEstablishing a comprehensive HP produced significant improvement in the severity of maternal hemorrhage and a significant reduction in blood product utilization. Widespread implementation of similar protocols should significantly improve patient safety and utilization of scarce resources. ObjectiveTo address patient safety and a source of major obstetrical morbidity, we initiated a comprehensive maternal hemorrhage protocol (HP). The objective of this study was to determine if the HP reduced the severity of OB hemorrhage, the number patients requiring transfusion or the number of units transfused. To address patient safety and a source of major obstetrical morbidity, we initiated a comprehensive maternal hemorrhage protocol (HP). The objective of this study was to determine if the HP reduced the severity of OB hemorrhage, the number patients requiring transfusion or the number of units transfused. Study DesingThe key elements of the HP are: admission risk assessment, measurement of blood loss, early uterotonics use, early obstetrician and anesthesiologist presence, and activation of key ancillary hospital personnel. The severity of hemorrhage was based on a 3 stage system: Stage 1=bleeding greater than expected; Stage 2=bleeding not responding to conservative treatment; Stage 3=continued bleeding with actual or expected blood loss to exceed 1500 cc. At Stage 3, fixed ratios of blood products were immediately released (RBC, FFP, Cryo, Plts). Patients activated to each stage were prospectively collected 4 months prior to, and in three 4-month time periods post-HP. The total number of patients receiving blood products and the number of units transfused was compared during the 12-month time period prior to, and after, the HP was initiated. Data was analyzed by T-test and ANOVA. The key elements of the HP are: admission risk assessment, measurement of blood loss, early uterotonics use, early obstetrician and anesthesiologist presence, and activation of key ancillary hospital personnel. The severity of hemorrhage was based on a 3 stage system: Stage 1=bleeding greater than expected; Stage 2=bleeding not responding to conservative treatment; Stage 3=continued bleeding with actual or expected blood loss to exceed 1500 cc. At Stage 3, fixed ratios of blood products were immediately released (RBC, FFP, Cryo, Plts). Patients activated to each stage were prospectively collected 4 months prior to, and in three 4-month time periods post-HP. The total number of patients receiving blood products and the number of units transfused was compared during the 12-month time period prior to, and after, the HP was initiated. Data was analyzed by T-test and ANOVA. ResultsDuring the study period there were 5813 deliveries. The maternal hemorrhage rate (Stage 1-3) was 4.9%. Relative to pre-HP, fewer patients required Stage 2 intervention post-HP (53%→18%, P=0.02) and more patients were succesfully treated at Stage 1 (35%→82%, p=0.02). There was a trend towards a reduction of patients requiring Stage 3 intervention post-HP (p=0.08). Although the number of patients reaching Stage 3 was not significantly lower, the units of blood products transfused in the 12 months pre-HP was significantly higher than the 12 month Post-HP (16.7→ 6.3 units/month, p<0.01). During the study period there were 5813 deliveries. The maternal hemorrhage rate (Stage 1-3) was 4.9%. Relative to pre-HP, fewer patients required Stage 2 intervention post-HP (53%→18%, P=0.02) and more patients were succesfully treated at Stage 1 (35%→82%, p=0.02). There was a trend towards a reduction of patients requiring Stage 3 intervention post-HP (p=0.08). Although the number of patients reaching Stage 3 was not significantly lower, the units of blood products transfused in the 12 months pre-HP was significantly higher than the 12 month Post-HP (16.7→ 6.3 units/month, p<0.01). ConclusionsEstablishing a comprehensive HP produced significant improvement in the severity of maternal hemorrhage and a significant reduction in blood product utilization. Widespread implementation of similar protocols should significantly improve patient safety and utilization of scarce resources. Establishing a comprehensive HP produced significant improvement in the severity of maternal hemorrhage and a significant reduction in blood product utilization. Widespread implementation of similar protocols should significantly improve patient safety and utilization of scarce resources." @default.
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- W4247443318 date "2011-01-01" @default.
- W4247443318 modified "2023-10-14" @default.
- W4247443318 title "142: Comprehensive maternal hemorrhage protocols improve patient safety and reduce utilization of blood products" @default.
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