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- W4247485700 abstract "Objective To determine whether the levonorgestrel-releasing intrauterine device (LNG-IUS), licensed at present for contraceptive use, may reduce menstrual blood loss with few side effects. If effective, surgery could be avoided with consequent resource savings. Methods A systematic review addressing the effectiveness and cost effectiveness of the LNG-IUS for menorrhagia was undertaken. Results Five controlled trials and five case series were found which measured menstrual blood loss. Nine studies recorded statistically significant average menstrual blood loss reductions with LNG-IUS (range 74%–97%). Another showed reduction in menstrual disturbance score. The LNG-IUS was more effective than tranexamic acid, but slightly less effective than endometrial resection at reducing menstrual blood loss. In one study, 64% of women cancelled surgery at six months, compared with 14% of control group women. In another, 82% were taken off surgical waiting lists at one year. No cost effectiveness studies were found. Discussion Small studies of moderate quality indicate the LNG-IUS is an effective treatment for menorrhagia. Costs may be less than for tranexamic acid in primary and secondary care. Although its use may reduce surgical waiting lists, cost effectiveness assessment requires longer follow up. Conclusion Effectiveness and cost effectiveness relative to other treatments and the effect on surgical waiting lists can only be established in larger trials measuring patient-centred outcomes in women with menorrhagia." @default.
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- W4247485700 date "2001-01-01" @default.
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- W4247485700 title "The effectiveness of the levonorgestrel-releasing intrauterine system in menorrhagia: a systematic review" @default.
- W4247485700 cites W1529006820 @default.
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- W4247485700 cites W1966511822 @default.
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- W4247485700 cites W1971184127 @default.
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- W4247485700 cites W2007749187 @default.
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- W4247485700 cites W2012165536 @default.
- W4247485700 cites W2015334359 @default.
- W4247485700 cites W2017237201 @default.
- W4247485700 cites W2018000086 @default.
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- W4247485700 cites W2031357322 @default.
- W4247485700 cites W2031785143 @default.
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- W4247485700 doi "https://doi.org/10.1016/s0306-5456(00)00020-6" @default.
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