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- W4247518787 abstract "Background: Impulsivity refers to a set of traits that are generally negatively related to critical domains of adaptive functioning and are core features of numerous psychiatric disorders. Methods: The current study examined the gray and white matter correlates of five impulsive traits measured using an abbreviated version of the UPPS-P impulsivity scale in children aged 9 to 10 (N = 11,052) from the Adolescent Brain and Cognitive Development (ABCD) study. Linear mixed effect models and elastic net regression were used to examine features of regional gray matter and white matter tractography most associated with each UPPS-P scale; intraclass correlations were computed to examine the similarity of the neuroanatomical correlates among the scales. Results: Positive Urgency showed the most robust association with neuroanatomy, with similar but less robust associations found for Negative Urgency. Perseverance showed little association with neuroanatomy. Premeditation and Sensation Seeking showed intermediate associations with neuroanatomy. Critical regions across measures include the dorsolateral prefrontal cortex, lateral temporal cortex, and orbitofrontal cortex; critical tracts included the superior longitudinal fasciculus and inferior fronto-occipital fasciculus. Negative Urgency and Positive Urgency showed the greatest neuroanatomical similarity. Conclusions: Some UPPS-P traits share neuroanatomical correlates, while others have distinct correlates or essentially no relation to neuroanatomy. UPPS-P traits tended to account for relatively little variance in neuroanatomy (i.e., model R2 < 1%) and effects were spread throughout the brain, highlighting the importance of well powered samples." @default.
- W4247518787 created "2022-05-12" @default.
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- W4247518787 date "2020-02-28" @default.
- W4247518787 modified "2023-09-27" @default.
- W4247518787 title "Neuroanatomical correlates of impulsive traits in children aged 9 to 10" @default.
- W4247518787 doi "https://doi.org/10.31234/osf.io/crbd4" @default.
- W4247518787 hasPublicationYear "2020" @default.
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