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- W4247550668 abstract "<h3>To the Editor.—</h3> I have read the recent article by Milton L. Levine, MD, entitled Cimetidine-Induced Coma in Cirrhosis of the Liver (240:1238, 1978), and I am somewhat surprised by such tenuous speculation. The article actually concludes that cimetidine may be the cause of hepatic coma in patients with liver cirrhosis simply because coma developed in a patient with a bleeding ulcer when given three doses of cimetidine. It is common knowledge that some patients with cirrhosis who bleed will have development of hepatic coma. This patient had cirrhosis of the liver, bled 7 g of hemoglobin acutely into the gut, had an elevated serum ammonia level, and had typical hepatic coma. Many physicians skim only the title of an article, and many such readers will unfortunately be left with the impression that cimetidine causes hepatic coma. This could certainly be far from the truth and an unproved and unfair" @default.
- W4247550668 created "2022-05-12" @default.
- W4247550668 date "1979-01-05" @default.
- W4247550668 modified "2023-09-26" @default.
- W4247550668 doi "https://doi.org/10.1001/jama.241.1.28" @default.
- W4247550668 hasPublicationYear "1979" @default.
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