Matches in SemOpenAlex for { <https://semopenalex.org/work/W4247580021> ?p ?o ?g. }
Showing items 1 to 74 of
74
with 100 items per page.
- W4247580021 endingPage "125" @default.
- W4247580021 startingPage "118" @default.
- W4247580021 abstract "Synthesis and biological evaluation of a novel series of substituted pentacyclic triterpene derivatives as potential PPARγ agoinsts and glycogen phosphorylase inhibitors have been described. Compounds 11 and 17 showed potent PPARγ agonistic activity and activated the transcription activity of PPARγ in a dose-dependent manner. On the other hand, eleven compounds exhibited moderate inhibitory activity against rabbit muscle glycogen phosphorylase a (RMGPa), and triterpene 10 was the best one. Structure-activity relationship (SAR) is also discussed. Keywords: Diabetes, Glycogen phosphorylase inhibitors, Oleanolic acid, PPARγ agonists, Pentacyclic triterpene, Ursolic acid" @default.
- W4247580021 created "2022-05-12" @default.
- W4247580021 creator A5003128598 @default.
- W4247580021 creator A5020415816 @default.
- W4247580021 creator A5024176882 @default.
- W4247580021 creator A5027835055 @default.
- W4247580021 creator A5052874928 @default.
- W4247580021 creator A5054451127 @default.
- W4247580021 creator A5079954554 @default.
- W4247580021 date "2012-11-01" @default.
- W4247580021 modified "2023-10-13" @default.
- W4247580021 title "Synthesis and Biological Evaluation of Novel Pentacyclic Triterpene Derivatives as Potential PPARγ Agonists" @default.
- W4247580021 doi "https://doi.org/10.2174/1573406411309010118" @default.
- W4247580021 hasPublicationYear "2012" @default.
- W4247580021 type Work @default.
- W4247580021 citedByCount "0" @default.
- W4247580021 crossrefType "journal-article" @default.
- W4247580021 hasAuthorship W4247580021A5003128598 @default.
- W4247580021 hasAuthorship W4247580021A5020415816 @default.
- W4247580021 hasAuthorship W4247580021A5024176882 @default.
- W4247580021 hasAuthorship W4247580021A5027835055 @default.
- W4247580021 hasAuthorship W4247580021A5052874928 @default.
- W4247580021 hasAuthorship W4247580021A5054451127 @default.
- W4247580021 hasAuthorship W4247580021A5079954554 @default.
- W4247580021 hasConcept C142724271 @default.
- W4247580021 hasConcept C170493617 @default.
- W4247580021 hasConcept C185592680 @default.
- W4247580021 hasConcept C187345961 @default.
- W4247580021 hasConcept C204779464 @default.
- W4247580021 hasConcept C204787440 @default.
- W4247580021 hasConcept C206103511 @default.
- W4247580021 hasConcept C2777499176 @default.
- W4247580021 hasConcept C2778858181 @default.
- W4247580021 hasConcept C2779513101 @default.
- W4247580021 hasConcept C2780527577 @default.
- W4247580021 hasConcept C43617362 @default.
- W4247580021 hasConcept C55493867 @default.
- W4247580021 hasConcept C71240020 @default.
- W4247580021 hasConcept C71924100 @default.
- W4247580021 hasConceptScore W4247580021C142724271 @default.
- W4247580021 hasConceptScore W4247580021C170493617 @default.
- W4247580021 hasConceptScore W4247580021C185592680 @default.
- W4247580021 hasConceptScore W4247580021C187345961 @default.
- W4247580021 hasConceptScore W4247580021C204779464 @default.
- W4247580021 hasConceptScore W4247580021C204787440 @default.
- W4247580021 hasConceptScore W4247580021C206103511 @default.
- W4247580021 hasConceptScore W4247580021C2777499176 @default.
- W4247580021 hasConceptScore W4247580021C2778858181 @default.
- W4247580021 hasConceptScore W4247580021C2779513101 @default.
- W4247580021 hasConceptScore W4247580021C2780527577 @default.
- W4247580021 hasConceptScore W4247580021C43617362 @default.
- W4247580021 hasConceptScore W4247580021C55493867 @default.
- W4247580021 hasConceptScore W4247580021C71240020 @default.
- W4247580021 hasConceptScore W4247580021C71924100 @default.
- W4247580021 hasIssue "1" @default.
- W4247580021 hasLocation W42475800211 @default.
- W4247580021 hasOpenAccess W4247580021 @default.
- W4247580021 hasPrimaryLocation W42475800211 @default.
- W4247580021 hasRelatedWork W1973494027 @default.
- W4247580021 hasRelatedWork W1980489695 @default.
- W4247580021 hasRelatedWork W2005802151 @default.
- W4247580021 hasRelatedWork W2022455474 @default.
- W4247580021 hasRelatedWork W2026117471 @default.
- W4247580021 hasRelatedWork W2028278049 @default.
- W4247580021 hasRelatedWork W2062948925 @default.
- W4247580021 hasRelatedWork W2525457827 @default.
- W4247580021 hasRelatedWork W2594481155 @default.
- W4247580021 hasRelatedWork W976894217 @default.
- W4247580021 hasVolume "9" @default.
- W4247580021 isParatext "false" @default.
- W4247580021 isRetracted "false" @default.
- W4247580021 workType "article" @default.