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- W4247616583 abstract "Current Protocols in PharmacologyVolume 85, Issue 1 e51 ISSUE INFORMATIONFree Access Issue Information TOC First published: 18 June 2019 https://doi.org/10.1002/cpph.51AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Graphical Abstract Cover: In Marchelletta et al. (https://doi.org/10.1002/cpph.54), the image show human colonic organoids retain in vivo morphology and cellular composition. Representative images of hematoxylin and eosin (H&E) staining of sections from paraffin-embedded organoids reveal a closed unit of differentiated columnar cells that resemble cells along the crypt axis in human colonic histologic sections from explant tissue. (A, B) Nuclei (dark purple) rest on the basal side in both explant tissue and organoids. (C-F) Organoids retain the cellular composition, frequency, and spatial orientation of tissue-resident colonic epithelial cells, as revealed by immunohistochemistry staining (arrows and brown staining) for the goblet-cell marker mucin 2 (MUC2) (C, D) and the enteroendocrine marker chromogranin A (E, F). View the latest in Pharmacology RelatedInformation" @default.
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- W4247616583 date "2019-06-01" @default.
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- W4247616583 doi "https://doi.org/10.1002/cpph.51" @default.
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