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- W4247644328 abstract "Ruhe bitte! Polysperminimidazol-4,5-imin (blaue Linien) wurde durch Kondensation von Spermin mit Bisformaldehydimidazol über eine pH-empfindliche Bindung erhalten und verwendet, um siRNAs zu Nanopartikeln zu kondensieren (siehe Schema) und ihren Transport in Zellen sowie die Freisetzung aus Endosomen zu untersuchen. Nach Zell- und In-vivo-Studien können mit diesem siRNA-Träger Zielgene mit vernachlässigbarer Cytotoxizität effizient ausgeschaltet werden." @default.
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- W4247644328 date "2012-07-16" @default.
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- W4247644328 title "Polyspermine Imidazole-4,5-imine, a Chemically Dynamic and Biologically Responsive Carrier System for Intracellular Delivery of siRNA" @default.
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- W4247644328 doi "https://doi.org/10.1002/ange.201201793" @default.
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