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- W4247711270 abstract "Physiologic EffectsNervous SystemThe general premise that anesthetics depress neuronal activity and interfere with synaptic transmission has been demonstrated with single units of excitable cells. The study of single-unit preparations provides information concerning membrane potential and excitability of the synaptic membrane. Although the organizational aspects of the central nervous system as they are affected by anesthetics cannot be determined, these studies are the first steps in attempts to understand the neural basis of anesthesia.Chalazonitis165 showed in the visceral ganglion of aplysia and nerve cells of helix that anesthetics, including halothane, chloroform and diethyl ether, hyperpolarize the synaptic membrane. . . ." @default.
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- W4247711270 date "1970-03-05" @default.
- W4247711270 modified "2023-10-17" @default.
- W4247711270 title "Pharmacologic and Physiologic Aspects of Anesthesiology" @default.
- W4247711270 doi "https://doi.org/10.1056/nejm197003052821006" @default.
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