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• W4247724107 abstract "Abstract Introduction: We sought to determine the diagnostic efficacy of BSGI in Chinese women with BI-RADS 4 category lesions and to compare this efficacy to that of ultrasound/mammography. Methods: We retrospectively assessed 177 women who had undergone BSGI of BI-RADS 4 category lesions detected via ultrasound and/or mammography. Results: Of the 177 cases, 117 (66.1%)were malignant lesions and 60(33.9%) were benign. The sensitivity, specificity, positive, and negative predictive values of BSGI were 94.9%(111/117), 78.3%(47/60), 89.5% (111/124), and 88.7%(47/53), respectively. For mammography, the specificity and positive predictive values were 48.3%(29/60) and 77.5% (107/138), while for ultrasound they were 53.3% (32/60) and 79.6% (109/137). The sensitivity and specificity of BSGI for the detection lesions ≤1 cm were 90.9% (10/11) and 88.0%(22/25), while these values for breast lesions ＞1cm were 94.3%(100/106) and 71.4% (25/35), and these values for dense breast tissue were 94.0%(79/84)and 78.0%(39/50), as opposed to non-dense breast values of 97.0%(32/33) and 80.0%(8/10). The sensitivity of BSGI for IDC and DCIS were 98.9%(95/96)and 75.0%(9/12).The tumor to normal tissue ratio of BSGI for malignant lesions was significantly higher than that of benign lesions (2.18 + 1.17 vs 1.66 + 0.40, t =7.56, P ＜0.05). Conclusions: These results reveal that BSGI is highly sensitive, with good positive/negative predictive values. BSGI for IDC proved to be superior to DCIS for diagnosis of BI-RADS 4 category lesions as compared with ultrasound or mammography. BSGI showed perfect results in density breasts and lesions ≤ 1 cm in size. Keywords : Breast cancer; BSGI; Mammography; 99m Tc-MIBI; Ultrasound" @default.
• W4247724107 created "2022-05-12" @default.
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• W4247724107 date "2020-01-17" @default.
• W4247724107 modified "2023-10-17" @default.
• W4247724107 title "Comparison of 99mTc-MIBI, ultrasound, and mammography for the diagnosis of BI-RADS 4 category lesions" @default.
• W4247724107 doi "https://doi.org/10.21203/rs.2.21106/v1" @default.
• W4247724107 hasPublicationYear "2020" @default.
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