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- W4248180828 abstract "Platelets from normal and malignant hyperthermia (MH)-susceptible pigs were evaluated for differences in 45calcium uptake in the absence or presence of caffeine (2–16 mM), halothane (0.05–0.5%), or halothane and caffeine together. There were no statistically significant differences in basal or halothane-inhibited calcium uptake by platelets from either source. There was a small statistically significant difference in calcium uptake between platelets from normal and MH-susceptible pigs in the presence of 16 mM caffeine and 0.5% halothane. Calcium uptake by platelets from one pedigree of MH-susceptible pigs were stimulated in a concentration-dependent manner by caffeine. These data suggest that exposure of platelets to caffeine may have potential for identifying MH-susceptiblity." @default.
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- W4248180828 date "1983-08-01" @default.
- W4248180828 modified "2023-09-26" @default.
- W4248180828 title "Malignant hyperthermia" @default.
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- W4248180828 doi "https://doi.org/10.1016/0006-2952(83)90174-0" @default.
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