Matches in SemOpenAlex for { <https://semopenalex.org/work/W4248289089> ?p ?o ?g. }
Showing items 1 to 76 of
76
with 100 items per page.
- W4248289089 endingPage "S73" @default.
- W4248289089 startingPage "S73" @default.
- W4248289089 abstract "The relative efficacies of 240 mg/day diltiazem and 20 mg/day nitrendipine were compared in a placebo-controlled, randomized, crossover study of 48 patients who had both moderate systemic hypertension and stable angina pectoris. Hemodynamic indices were measured by impedance cardiography and echocardiography and bicycle ergometry was performed. Compared with placebo, both diltiazem and nitrendipine decreased systolic (p < 0.05 for both) and diastolic (p < 0.05 for both) blood pressure, the total peripheral vascular resistance (p < 0.01 for both), the frequency of anginal attacks (p < 0.001 for both) and nitroglycerin usage (p < 0.01 for both), and increased exercise duration (p < 0.01 and p < 0.05), exercise time to angina (p < 0.01 and p < 0.05) and time to the onset of ST-segment deviation) (p < 0.01 and p < 0.05). There were no significant differences in the antihypertensive and antianginal effects of the two drugs. Resting heart rate was increased from placebo baseline with nitrendipine (p < 0.01) during the first week of the treatment, and the reduction of the rate-pressure product and the decrease of the left ventricular mass were greater using diltiazem (p < 0.05). Sixteen patients had insufficient responses to monotherapy and continued in the study for additional treatment with the combination 120 mg/day diltiazem and 20 mg/day nitrendipine. The normalization of diastolic blood pressure was achieved and more pronounced rate-pressure product reduction was found. No additional side effects were mentioned. Diltiazem and, especially, the combination of diltiazem and nitrendipine is an effective and safe therapy for patients with both systemic hypertension and stable angina pectoris." @default.
- W4248289089 created "2022-05-12" @default.
- W4248289089 creator A5024713445 @default.
- W4248289089 creator A5060953744 @default.
- W4248289089 creator A5071903331 @default.
- W4248289089 creator A5071983006 @default.
- W4248289089 date "1991-01-01" @default.
- W4248289089 modified "2023-09-30" @default.
- W4248289089 title "Comparison of Diltiazem, Nitrendipine, and Their Combination for Systemic Hypertension and Stable Angina Pectoris" @default.
- W4248289089 doi "https://doi.org/10.1097/00005344-199106189-00016" @default.
- W4248289089 hasPublicationYear "1991" @default.
- W4248289089 type Work @default.
- W4248289089 citedByCount "5" @default.
- W4248289089 countsByYear W42482890892012 @default.
- W4248289089 crossrefType "journal-article" @default.
- W4248289089 hasAuthorship W4248289089A5024713445 @default.
- W4248289089 hasAuthorship W4248289089A5060953744 @default.
- W4248289089 hasAuthorship W4248289089A5071903331 @default.
- W4248289089 hasAuthorship W4248289089A5071983006 @default.
- W4248289089 hasBestOaLocation W42482890891 @default.
- W4248289089 hasConcept C126322002 @default.
- W4248289089 hasConcept C142724271 @default.
- W4248289089 hasConcept C164705383 @default.
- W4248289089 hasConcept C178853913 @default.
- W4248289089 hasConcept C204787440 @default.
- W4248289089 hasConcept C27081682 @default.
- W4248289089 hasConcept C2776741139 @default.
- W4248289089 hasConcept C2777953023 @default.
- W4248289089 hasConcept C2778425758 @default.
- W4248289089 hasConcept C2780548744 @default.
- W4248289089 hasConcept C42219234 @default.
- W4248289089 hasConcept C500558357 @default.
- W4248289089 hasConcept C519063684 @default.
- W4248289089 hasConcept C57900726 @default.
- W4248289089 hasConcept C71316499 @default.
- W4248289089 hasConcept C71924100 @default.
- W4248289089 hasConcept C84393581 @default.
- W4248289089 hasConcept C87813604 @default.
- W4248289089 hasConceptScore W4248289089C126322002 @default.
- W4248289089 hasConceptScore W4248289089C142724271 @default.
- W4248289089 hasConceptScore W4248289089C164705383 @default.
- W4248289089 hasConceptScore W4248289089C178853913 @default.
- W4248289089 hasConceptScore W4248289089C204787440 @default.
- W4248289089 hasConceptScore W4248289089C27081682 @default.
- W4248289089 hasConceptScore W4248289089C2776741139 @default.
- W4248289089 hasConceptScore W4248289089C2777953023 @default.
- W4248289089 hasConceptScore W4248289089C2778425758 @default.
- W4248289089 hasConceptScore W4248289089C2780548744 @default.
- W4248289089 hasConceptScore W4248289089C42219234 @default.
- W4248289089 hasConceptScore W4248289089C500558357 @default.
- W4248289089 hasConceptScore W4248289089C519063684 @default.
- W4248289089 hasConceptScore W4248289089C57900726 @default.
- W4248289089 hasConceptScore W4248289089C71316499 @default.
- W4248289089 hasConceptScore W4248289089C71924100 @default.
- W4248289089 hasConceptScore W4248289089C84393581 @default.
- W4248289089 hasConceptScore W4248289089C87813604 @default.
- W4248289089 hasLocation W42482890891 @default.
- W4248289089 hasLocation W42482890892 @default.
- W4248289089 hasOpenAccess W4248289089 @default.
- W4248289089 hasPrimaryLocation W42482890891 @default.
- W4248289089 hasRelatedWork W2022397683 @default.
- W4248289089 hasRelatedWork W2055279203 @default.
- W4248289089 hasRelatedWork W2093346357 @default.
- W4248289089 hasRelatedWork W2108673207 @default.
- W4248289089 hasRelatedWork W2129708432 @default.
- W4248289089 hasRelatedWork W2407817793 @default.
- W4248289089 hasRelatedWork W2431166994 @default.
- W4248289089 hasRelatedWork W2464539840 @default.
- W4248289089 hasRelatedWork W2518842539 @default.
- W4248289089 hasRelatedWork W2979951955 @default.
- W4248289089 hasVolume "18" @default.
- W4248289089 isParatext "false" @default.
- W4248289089 isRetracted "false" @default.
- W4248289089 workType "article" @default.