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- W4248308544 abstract "In peevious report we observed that the antihormone against HCG was produced in cattle receiving large amounts of this hormone. The dosage of HCG used in the previous experiment, however, was much more than that used generally for the purpose of treating ovarian disorders in cattle. In this paper an attempt was undertaken to ascertain whether the Anti-HCG was produced in cattle which had been injected repeatedly with general dosage of HCG. Serum samples collected from 11 cows with cystic ovaries were used as materials to determine the Anti-HCG. The methods to determine the Anti-HCG in the serum samples were same as described in the previous report. These animals had been injected 13 times with 5, 000 IU-20, 000 MU of HCG for treating ovarian cysts. The treating histories, prognosis and ovarian conditions of these animals and the results of the Anti-HCG determinations are shown in Table 1. The Anti-HCG determinations were also performed on the serum samples collected from 11 control animals which had not been injected with HCG within recent 12 months. The ovarian conditions and the results of the Anti-HCG determinations on the control animals are shown in Table 2. The results obtained were smumarized as follows:1. In 6 of 11 cows which had been received 13 injections of 5, 00020, 000 MU or 5, 00010, 000 IU of HCG intramuscularly within recent 4 months in order to treat ovarian cysts, the serum Anti-HCG was determined to be positive. The HCG inhibiting titers of these positive sera were 1.5 MU-24.0 MU or more per cc. The Anti-HCG positive animals did not recover from ovarian cysts in spite of the HCG treatments for 13 times.On the contrary, in 15 animals in which the serum Anti-HCG was determined to be negative, 2 animals had recovered from ovarian cysts and came in normal estrous cycle and 2 were recovering from ovarian cysts by the HCG treatments. Only one animal was not yet restored by the treatments.From these results, it is possible that the Anti-HCG in produced in considerable number of cattle with cystic ovaries which were uncurable following repeated treatments with HCG. 2. On all of the serum samples from 11 control animals, including 5 with cystic ovaries, 3 with ovarian dysfunctions and 3 with normal estrous cycles, the Anti-HCG was determined to be negative.From these results, it is quite possible that the Anti-HCG is not produced in cattle which have not been injected with HCG." @default.
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- W4248308544 date "1961-01-01" @default.
- W4248308544 modified "2023-10-14" @default.
- W4248308544 title "Studies on the antihormone against human chorionic gonadotrophin (Anti-HCG) in cattle" @default.
- W4248308544 doi "https://doi.org/10.1262/jrd1955.7.32" @default.
- W4248308544 hasPublicationYear "1961" @default.
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