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- W4248791337 abstract "Two principal pathways for apoptosis initiation exist. One pathway, which is also termed the ‘extrinsic’ pathway, is mediated by death receptors, a subgroup of the TNF receptor superfamily. The second pathway, which is also referred to as the ‘intrinsic’ pathway is controlled by members of the Bcl-2 family. A long standing discussion revolves around the question of how these two pathways influence each other in regulating the decision about life or death of a cell. Here, we review our current knowledge about the interactions between these two pathways and discuss current models which could help to resolve previous apparently contradictory results." @default.
- W4248791337 created "2022-05-12" @default.
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- W4248791337 date "2004-03-01" @default.
- W4248791337 modified "2023-09-26" @default.
- W4248791337 title "The interplay between the Bcl-2 family and death receptor-mediated apoptosis" @default.
- W4248791337 doi "https://doi.org/10.1016/s0167-4889(03)00179-4" @default.
- W4248791337 hasPublicationYear "2004" @default.
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