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- W4248903913 abstract "Today, the huge variety of nanoparticles and nanocarriers proposed to be applied in foods as nanodelivery systems create urgency to detect and characterize their mode of action in the human body regarding their release profiles and bioavailability. For this purpose, both in vitro and in vivo methods have been widely utilized. Despite the necessity of in vitro tests in preliminary steps, in vivo assays are much more reliable due to using live organisms. In vivo assays investigate the proficiency of nanoencapsulation in protection and transformation of bioactive food ingredients into the target cells, and also the biocompatibility between nanoparticles and host organs. This chapter gives a comprehensive description of the in vivo assays that have been used for performance-based assessment of nanoencapsulated food ingredients so far. In this regard, the functionality and applicability of nanodelivery systems are initially discussed. Further, the release mechanism and bioavailability of nanoencapsulated food ingredients are presented. Subsequently, the efficiency of bioactive-loaded nanocarriers through both in vitro and in vivo studies is provided. Furthermore, common model organisms for in vivo assays are introduced, and finally, the limitations of in vivo assays are discussed." @default.
- W4248903913 created "2022-05-12" @default.
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- W4248903913 date "2020-01-01" @default.
- W4248903913 modified "2023-09-30" @default.
- W4248903913 title "In vivo assays for evaluating the release of nanoencapsulated food ingredients" @default.
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- W4248903913 doi "https://doi.org/10.1016/b978-0-12-815665-0.00005-9" @default.
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